Indium(III)+phosphate
Supplier:
BeanTown Chemical
Description:
CAS: 124-18-5; EC No: 204-686-4; MDL No: MFCD00008954; RTECS: HD6550000
UN No: UN2247; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: CH3(CH2)8CH3; Molecular Formula: C10H22; MW: 142.29
Melting Point: -30°; Boiling Point: 168-178°; Flash point: 46°C (115°F)
Density (g/mL): 0.73; Refractive Index: 1.411
Supplier:
BeanTown Chemical
Description:
CAS: 108-67-8; EC No: 203-604-4; MDL No: MFCD00008538; RTECS: OX6825000
UN No: UN2325; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: C6H3(CH3)3; Molecular Formula: C9H12; MW: 120.20
Melting Point: -45°; Boiling Point: 163-166°; Flash point: 44°C (111°F)
Density (g/mL): 0.864; Refractive Index: 1.499
Supplier:
BeanTown Chemical
Description:
CAS: 2269-22-9; EC No: 218-871-2; MDL No: MFCD00009327
UN No: UN1992; Haz Class: 3 (6.1); Packing Group: III
Liquid; Linear Formula: Al[OCH(CH3)CH2CH3]3; Molecular Formula: C12H27AlO3; MW: 246.32
Boiling Point: 200-206°/30 mmHg; Flash point: 26°C (79°F)
Density (g/mL): 0.967
Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 107-08-4; EC No: 203-460-2; MDL No: MFCD00001095; RTECS: TZ4100000
UN No: UN2392; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: CH3CH2CH2I; Molecular Formula: C3H7I; MW: 169.99
Melting Point: -101°; Boiling Point: 101-102°; Flash point: 44°C (111°F)
Density (g/mL): 1.743; Refractive Index: 1.504
Light Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 71-41-0; EC No: 200-752-1; MDL No: MFCD00002977; RTECS: SB9800000
UN No: UN1105; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: CH3(CH2)4OH; Molecular Formula: C5H12O; MW: 88.15
Melting Point: -78°; Boiling Point: 136-138°; Flash point: 49°C (120°F)
Density (g/mL): 0.811; Refractive Index: 1.409
Catalog Number:
(10111-622)
Supplier:
Prosci
Description:
AGPAT2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance.This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Catalog Number:
(76264-640)
Supplier:
Biosensis
Description:
Peripherin is a class-III neuronal intermediate filament protein found in certain classes of neuron, most of which are located in the peripheral nervous system. Antibody reacts with rat. The specificity of this antibody has been confirmed by WB. This antibody detects ~57 kDa Peripherin protein. Cross-reacts with Human, mouse, feline. Predicted to react with other mammalian tissue.
Supplier:
BeanTown Chemical
Description:
CAS: 95-54-5; EC No: 202-430-6; MDL No: MFCD00007721; RTECS: SS7875000
UN No: UN1673; Haz Class: 6.1; Packing Group: III
Solid; Linear Formula: C6H4(NH2)2; Molecular Formula: C6H8N2; MW: 108.14
Melting Point: 98-102°; Boiling Point: 256-258°; Flash point: 136°C (277°F)
Density (g/mL): 1.03
Moisture Sensitive
Catalog Number:
(10070-922)
Supplier:
Prosci
Description:
Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3, 4, 5-trisphosphate, phosphatidylinositol 3, 4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1, 3, 4, 5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3, 4, 5)P3 > PtdIns(3, 4)P2 > PtdIns3P > Ins(1, 3, 4, 5)P4. The lipid phosphatase activity is critical for its tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation. Dephosphorylates tyrosine-phosphorylated focal adhesion kinase and inhibits cell migration and integrin-mediated cell spreading and focal adhesion formation. May be a negative regulator of insulin signaling and glucose metabolism in adipose tissue.
Catalog Number:
(10068-814)
Supplier:
Prosci
Description:
Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3, 4, 5-trisphosphate, phosphatidylinositol 3, 4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1, 3, 4, 5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3, 4, 5)P3 > PtdIns(3, 4)P2 > PtdIns3P > Ins(1, 3, 4, 5)P4. The lipid phosphatase activity is critical for its tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation. Dephosphorylates tyrosine-phosphorylated focal adhesion kinase and inhibits cell migration and integrin-mediated cell spreading and focal adhesion formation. May be a negative regulator of insulin signaling and glucose metabolism in adipose tissue.
Supplier:
BeanTown Chemical
Description:
CAS: 3886-69-9; EC No: 223-423-4; MDL No: MFCD00064405
UN No: UN2735; Haz Class: 8; Packing Group: III
Liquid; Molecular Formula: C8H11N; MW: 121.18
Boiling Point: 187-189°; Flash point: 70°C (158°F)
Density (g/mL): 0.952; Refractive Index: 1.526; Optical Rotation: [α]23/D +38°, neat
Air Sensitive
Catalog Number:
(IC15188601)
Supplier:
MP Biomedicals
Description:
Reconstitution: Reconstitute with water to a final concentration of 1 mg/mL (use 1 mL for the 1 mg size or 5 mL for the 5 mg size) for a final solution of 1 mg/mL in 0.40 mM sodium phosphate, 6 mM NaCl, pH 7.45. Reconstitute with water to a final concentration of 25 mg/mL (0.2 ml water for the 5 mg size). This concentration of the lectin has been used for iontophoresis and neuron transport.
Supplier:
Biotium
Description:
This MAb recognizes a protein of 165 kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Supplier:
Biotium
Description:
This MAb recognizes a protein of 165 kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Supplier:
BeanTown Chemical
Description:
CAS: 865-49-6; EC No: 212-742-4; MDL No: MFCD00000827
UN No: UN1888; Haz Class: 6.1; Packing Group: III
Liquid, in prescored ampules, 0.75ml/ampule ; Molecular Formula: CDCl3; MW: 120.38
Melting Point: -64°; Boiling Point: 60.9°
Density (g/mL): 1.5; Refractive Index: 1.444
Light Sensitive, Moisture Sensitive
Catalog Number:
(76118-720)
Supplier:
Bioss
Description:
Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.
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