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4-Bromo-2-fluorophenyl+isothiocyanate
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4-Bromo-2-fluorophenyl+isothiocyanate
Supplier:
BeanTown Chemical
Description:
CAS: 7378-99-6; EC No: 230-939-3; MDL No: MFCD00009558
UN No: UN2922; Haz Class: 8 (6.1); Packing Group: III
Liquid; Linear Formula: CH3(CH2)7N(CH3)2; Molecular Formula: C10H23N; MW: 157.30
Melting Point: -57°; Boiling Point: 195°; Flash point: 64°C (147°F)
Density (g/mL): 0.765; Refractive Index: 1.424
Air Sensitive
Catalog Number:
(10393-916)
Supplier:
Bioss
Description:
In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Catalog Number:
(10393-920)
Supplier:
Bioss
Description:
In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Catalog Number:
(76121-062)
Supplier:
Bioss
Description:
WDFY3 was identified in a screen for phosphatidylinositol 3 phosphate binding proteins. The FYVE domain is a zinc binding domain found in many PtdIns binding proteins and is proposed to target proteins to membrane lipids. WDFY3 has been shown localized to the nuclear membrane and within autophagic membranes and it is proposed to function as a link between protein aggregates and the autophagic machinery. WDFY3 is also known as autophagy linked FYVE protein.
Catalog Number:
(MSPP-WEA176HU)
Supplier:
CLOUD-CLONE CORP MS
Description:
This assay has high sensitivity and excellent specificity for detecting Human COL3 (Collagen Type III). The assay range is from 0.625 to 40 ng/ml (Sandwich kit) with a sensitivity of 0.264 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
Catalog Number:
(MSPP-CEG031GE)
Supplier:
CLOUD-CLONE CORP MS
Description:
This assay has high sensitivity and excellent specificity for detecting General species S1P (Sphingosine to 1-Phosphate). The assay range is from 12.35 to 1000 ng/ml (Competitive kit) with a sensitivity of 4.62 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
Catalog Number:
(75790-058)
Supplier:
Prosci
Description:
Interleukin-22 Receptor Subunit alpha-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Catalog Number:
(76193-624)
Supplier:
Prosci
Description:
PACS proteins are involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. PACS-1, or Phosphofurin acidic cluster sorting protein 1, is involved in protein sorting and ion channel trafficking. It directs the trans-Golgi network (TGN) localization of furin and M6PR (Mannose 6-phosphate receptor). PACS-1 also mediates the binding of VAMP4, a TGN-to-endosome transport protein, to AP-1.
Supplier:
BeanTown Chemical
Description:
CAS: 71-36-3; EC No: 200-751-6; MDL No: MFCD00002964; RTECS: EO1400000
UN No: UN1120; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: CH3(CH2)3OH; Molecular Formula: C4H10O; MW: 74.12
Melting Point: -90°; Boiling Point: 116-118°; Flash point: 35°C (95°F)
Density (g/mL): 0.81; Refractive Index: 1.399
Hygroscopic
Catalog Number:
(10473-408)
Supplier:
Bioss
Description:
This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish. The protein encoded by this gene interacts with maspardin, a protein that when truncated is responsible for Mast syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Catalog Number:
(10077-872)
Supplier:
Prosci
Description:
Sphingosine kinase (SPHK) phosphorylates sphingosine to form a bioactive lipid mediate, sphingosine 1-phosphate (S1P or SPP). S1P is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival while extracellularly it is a ligand for EDG 1. Expression of SPHK1 and subsequent production of S1P promotes the G1-S transition, protects cells from apoptosis, stimulates migration and angiogenesis, and induces tumor formation in mice.
Catalog Number:
(10764-668)
Supplier:
Prosci
Description:
The 3G8 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.
Catalog Number:
(10765-514)
Supplier:
Prosci
Description:
The CB16 monoclonal antibody specifically reacts with human CD16, the low affinity IgG receptor III (FC gamma RIII). CD16 is expressed on granulocytes, monocytes, macrophages, and NK cells and plays a role in NK activation and signal transduction. CD16 is expressed as either CD16a or CD16b. CD16a is a polypeptide-anchored transmembrane protein and CD16b is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed exclusively on neutrophils.
Supplier:
BeanTown Chemical
Description:
CAS: 6192-52-5; EC No: 203-180-0; MDL No: MFCD00142137; RTECS: XT6300000
UN No: UN2585; Haz Class: 8; Packing Group: III
Solid; Linear Formula: CH3C6H4SO3H·H2O; Molecular Formula: C7H8O3S·H2O; MW: 190.22
Melting Point: 103-106°; Boiling Point: 140°/22 mmHg; Flash point: 150°C (302°F)
Density (g/mL): 1.24
Hygroscopic
Catalog Number:
(10332-644)
Supplier:
Bioss
Description:
Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.
Catalog Number:
(MSPP-CEA573HU)
Supplier:
CLOUD-CLONE CORP MS
Description:
This assay has high sensitivity and excellent specificity for detecting Human PIIINP (Procollagen III N to Terminal Propeptide). The assay range is from 4.94 to 400 ng/ml (Competitive kit) with a sensitivity of 2.13 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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