4,4\'-Diaminodiphenyl+ether
Supplier:
Adipogen
Description:
Mubritinib is a potent, irreversible human epithelial growth factor receptor 2 (ErbB2/HER2) inhibitor (IC(50) of 6nM) which displays <gt/> 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src kinases.
Supplier:
Adipogen
Description:
XL765 is active against class I PI3K (IC(50) = 39, 113, 9 and 43nM for p110alpha, beta, gamma and delta, respectively). XL765 also inhibits DNA-PK (IC(50) = 150nM) and mTOR (IC(50) = 157nM)
Supplier:
Adipogen
Description:
Sulfonephthalein dye. Acid-base pH indicator dye with pH ranges of pH 1.2 (Red) - pH 2.8 (Yellow), and pH 8.0 (Yellow) - pH 9.6 (Blue). Spectral data: Absorption, lambdamax 424nm. Has been used as pH sensor, indicator, in cosmetics and drug applications, microbiological assays and determining lipases.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Alcohol, anhydrous, reagent made from specially denatured alcohol 3A.
Supplier:
Promega Corporation
Description:
The ReliaPrep gDNA Tissue Miniprep System provides a complete, ready-to-use method for purification of gDNA from up to 25mg of tissue, a buccal swab, or a 1cm mouse tail snip, obtaining intact gDNA without the use of ethanol washes or precipitations.
Catalog Number:
(MFLX96419-35)
Supplier:
VWR International
Description:
Long life tubing for any Masterflex® pump used in your pharma and bioprocess applications.
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Supplier:
Adipogen
Description:
NVP-BGT226 is a novel, orally bioavailable small-molecule inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin with an IC(50) of 1nM.
Supplier:
Adipogen
Description:
CI-1040 (PD184352) is an orally active, highly specific, small-molecule inhibitor of MEK1/2, which is a key component of the ERK/MAPK pathway. It has an IC(50) of 17nM.
Supplier:
Thermo Scientific Chemicals
Description:
Solvent, catalyst, strong non-oxidizing acid
Catalog Number:
(80108-306)
Supplier:
MilliporeSigma
Description:
An active metabolite of the nonsteroidal, anti-inflammatory drug sulindac (80058-684)
Supplier:
Adipogen
Description:
Potent cyclin-dependent kinase (CDK) 1, 2, 5, and 9 inhibitor. Apoptosis inducer. Inhibits the proliferation of various cancer cell lines. Inhibits cysts formation in culture. Casein kinase 1 (CK1delta/epsilon) and Dyrk1A inhibitor. Down regulates expression of Mcl-1 and MYCN. Neuroprotective in experimental traumatic brain injury. Potential anti-inflammatory compound. Potential antidiabetic compound.
Supplier:
Adipogen
Description:
GW441756 is an orally active, potent and highly selective TrkA tyrosine kinase inhibitor (IC(50) of 2nM). It specifically blocks TrkA-induced cell death in a dose-dependent manner.
Supplier:
Adipogen
Description:
Cell permeable, irreversible calmodulin antagonist. Acts by covalently binding to a lysine-rich inhibitory site. Inhibits by blocking the activation of the Ca2+/calmodulin-dependent phosphodiesterase. Herbicidal mycotoxin. Phytotoxic, antifungal, antibacterial and nematocidal compound. Anticancer compound. Shown to induce paraptosis-like cell death. Shown to inhibit P-glycoprotein-mediated transport.
Catalog Number:
(80053-430)
Supplier:
MilliporeSigma
Description:
Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t¹/₂ = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC50 = 130 nM).
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Made from Specially Denatured Alcohol 3A.
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