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Lead(II)+oxide
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Lead(II)+oxide
Catalog Number:
(10308-872)
Supplier:
Bioss
Description:
E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth.
Catalog Number:
(10106-918)
Supplier:
Prosci
Description:
PPARdelta is pivotal to control the program for fatty acid oxidation in the skeletal muscle, thereby ameliorating obesity and insulin resistance through its activation in obese animals.
Catalog Number:
(77439-766)
Supplier:
Bioss
Description:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Catalog Number:
(10408-432)
Supplier:
Bioss
Description:
Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
Catalog Number:
(10408-172)
Supplier:
Bioss
Description:
Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
Catalog Number:
(32031-161)
Supplier:
Sierra Monitor
Description:
This gas sensor is a compact, solidstate, fixed-installation single alarm monitor designed for continuous area monitoring of combustible gas.
Supplier:
Hirschmann
Description:
Dispensers feature a ceramic plunger that is made of solid, 99.7% pure aluminum oxide, which guarantees the highest degree of chemical resistance, without abrasion or swelling.
Supplier:
GE Healthcare - Whatman
Description:
Whatman Anotop non sterile syringe filters from Cytiva feature an inorganic Anopore membrane in a polypropylene housing.
Catalog Number:
(10458-106)
Supplier:
Bioss
Description:
Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Supplier:
VWR
Description:
One of the best general-purpose buffers for biological research. Excellent for tissue culture, oxidative phosphorylation, protein synthesis with cell-free bacterial systems, photophosphorylation, and CO<sub>2</sub> fixation.
Catalog Number:
(75931-766)
Supplier:
Rockland Immunochemical
Description:
The mitochondrial succinate dehydrogenase complex subunit D (SDHD) is one of four proteins that make up the tricarboxylic cycle enzyme succinate dehydrogenase (SCH). Studies have shown that mutations in SDHD often leads to hereditary paragangliomas, usually benign tumors of the autonomic nervous system, suggesting that SDHD also plays a role as a tumor-suppressor gene. In one family with a nonsense mutation (R22X) in the SDHD gene, a loss of heterozygosity was found in the paragangliomas, and within these tumors the enzymatic activity of Complex II in the mitochondrial respiratory chain was completely abolished. Furthermore, high levels of angiogenic factors EPAS1 and VEGF was observed, which may stimulate tumor growth.
Catalog Number:
(76117-396)
Supplier:
Bioss
Description:
Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Catalog Number:
(10752-228)
Supplier:
Prosci
Description:
Thioredoxin-interacting protein (TXNIP) belongs to the arrestin family and plays a critical role in the antioxidant defense mechanisms of hematopoietic cells by activating the p53 pathway during oxidative stress. It functions as a transcriptional repressor and acts as an oxidative stress mediator by inhibiting thioredoxin activity. TXNIP expression is reduced in many types of tumors, and TXNIP overexpression inhibits tumor growth by blocking cell-cycle progression. It has recently reported that TXNIP deficiency correlates with a high incidence of hepatocellular carcinoma (HCC). TXNIP and p53 interactions could potentially be a therapeutic target for oxidative stress-related diseases such as hematopoietic malignancies and metabolic diseases.
Catalog Number:
(76079-720)
Supplier:
Bioss
Description:
Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
Catalog Number:
(89146-982)
Supplier:
Enzo Life Sciences
Description:
Selective cell permeable inhibitor of PKCζ. Activates eNOS (NOS III) through Akt phosphorylation and can be considered as a nitric oxide production activator in endothelial cells.
Catalog Number:
(89495-090)
Supplier:
Genscript
Description:
THEâ„¢ NWSHPQFEK Tag antibody [Biotin], mAb, Mouse recognizes N-terminal and C-terminal Strep II tagged fusion proteins.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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