N'-[1-[(Furan-2-ylmethyl)amino]2-phenylethylidene]hydrazinecarbox
Supplier:
AOB CHEM USA
Description:
4-Chloro-3-methylbenzotrifluoride ≥95%
Supplier:
Matrix Scientific
Description:
MF=C10H10F3NO2 MW=233.19 CAS=65568-55-0 MDL=MFCD08274771 5G
Supplier:
AMBEED, INC
Description:
Ethyl-2-amino-4-trifluoromethylbenzoate 95%
Supplier:
Adipogen
Description:
The lymphocyte-specific kinase (Lck) is a cytoplasmic tyrosine kinase of the Src family expressed in T cells and natural killer (NK) cells. Genetic evidence in both mice and humans demonstrates that Lck kinase activity is critical for signaling mediated by the T cell receptor (TCR), which leads to normal T cell development and activation. Selective inhibition of Lck is expected to offer a new therapy for the treatment of T-cell-mediated autoimmune and inflammatory disease. AMG-47 is one of two optimized chemical compounds that has been shown to be extremely effective in vivo and in vitro in inhibiting Lck as well as a number of other receptor tyrosine kinases. In an anti-CD3/ IL-2 mouse model system AMG-47 has been shown to be effective in inhibiting the Lck mediated anti-inflammatory activity (ED50 11 mg/kg; 630nM) in vivo. In multiple other in vitro assays, AMG-47 exhibits subnanomolar inhibition against Lck, and low (<lt/>10nM) inhibition against other hard to inhibit kinases such as KDR and SRC and MAPK alpha (p38alpha). Moreover at slightly higher doses but well under 10µM, AMG-47 effectively inhibits the JNK family of kinases including TYK2 at ~ 1.2µM.
Supplier:
AMBEED, INC
Description:
Methyl-3,4,5-trihydroxybenzoate 98%
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Methyl-3,4,5-trihydroxybenzoate 99%
Supplier:
Thermo Scientific Chemicals
Description:
Gallic acid methyl ester Methyl 3,4,5-trihydroxybenzoate. Grade:98, Melting Point C200-202*. Boiling Point C:NA. C8H8O5. 99-24-1. HARMFUL IRRITANT
Catalog Number:
(BT130140-5G)
Supplier:
BeanTown Chemical
Description:
CAS: 507-52-8; EC No: 208-075-3; MDL No: MFCD00014391
UN No: UN1987; Haz Class: 3; Packing Group: II
Liquid; Molecular Formula: C4H7F3O; MW: 128.09
Boiling Point: 83°; Flash point: 15°C (59°F)
Density (g/mL): 1.17; Refractive Index: 1.334
Catalog Number:
(BDH2022-55GLP)
Catalog Number:
(BDH67006.400)
Supplier:
VWR International
Description:
BDH* 1-Methyl-2-pyrrolidinone, Chemical Formula: C5H9NO, Melting Point: -24, Boiling Point: 202, Flash Point: 95 deg C, Formula Weight: 99.13, CAS Number: 872-50-4, Grade: HPLC/Spectro, HiPerSolv CHROMANORM, Class: F, Size: 4L
Catalog Number:
(BDH67005.400)
Supplier:
VWR International
Description:
BDH* Methyl t-Butyl Ether, Chemical Formula: (CH3)3COCH3, Melting Point:, Boiling Point:, Flash Point: -32 deg C, Formula Weight:, CAS Number: 1634-04-4, Grade: HPLC/Spectro, HiPerSolv CHROMANORM, Class: F, Size: 4L
Supplier:
VWR International
Description:
BDH N-Methylpyrrolidone (Aka 1-Methyl-2-Pyrrolidone, Nmp) Is Suitable For General Laboratory Use Including Organic Synthesis, Cleaning, Prep Scale Synthesis. ACS Certified.
Catalog Number:
(BDH1139-4LG)
Catalog Number:
(BDH7388-2)
Supplier:
VWR International
Description:
Bromocresol green and methyl red in denatured alcohol (SDA-3A).
Catalog Number:
(TCG0017-100G)
Supplier:
TCI America
Description:
CAS Number: 99-24-1
MDL Number: MFCD00002194 Molecular Formula: C8H8O5 Molecular Weight: 184.15 Purity/Analysis Method: >98.0% (GC,T) Form: Crystal Melting point (°C): 200
Catalog Number:
(BDH25643.400)
Supplier:
VWR International
Description:
BDH* Methyl Ethyl Ketone, Chemical Formula: C4H8O, Melting Point: -86.6, Boiling Point: 79.5, Flash Point: -9 deg C, Formula Weight: 72.11, CAS Number: 78-93-3, Grade: HPLC/Spectro, HiPerSolv CHROMANORM, Class: F, Size: 4L
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