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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

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Supplier:  Matrix Scientific
Description:   MF=C7H3BRF3I MW=350.91 CAS=640280-28-0 MDL=MFCD09800691 5G

Supplier:  AFG BIOSCIENCE LLC
Description:   Chicken COL8a1 (Collagen Type VIII Alpha 1) ELISA Kit
Supplier:  Novus Biologicals
Description:   The CD25 / IL-2 R alpha Antibody (OX-39) [DyLight 680] from Novus Biologicals is a mouse monoclonal antibody to CD25 / IL-2 R alpha. This antibody reacts with rat. The CD25 / IL-2 R alpha Antibody (OX-39) [DyLight 680] has been validated for the following applications: Flow Cytometry, ELISA, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Supplier:  APOLLO SCIENTIFIC
Description:   3,4-Dichloro-α,α,α-trifluorotoluene 98%
Supplier:  Biotium
Description:   This antibody neutralises HurTNFamediated cytotoxicity of L929 cells and inhibits tumour growth in mice. It protects mice against toxicity of HurTNFa. Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Supplier:  Bioss
Description:   Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit. There are two alpha-adaptin genes, alpha A and alpha C which have a tissue specific pattern of expression.

Supplier:  Novus Biologicals
Description:   The DNA polymerase alpha Antibody from Novus Biologicals is a rabbit polyclonal antibody to DNA polymerase alpha. This antibody reacts with human. The DNA polymerase alpha Antibody has been validated for the following applications: Western Blot, Immunoprecipitation, Proximity Ligation Assay.

Supplier:  Novus Biologicals
Description:   The Proteasome 20S alpha 3 Antibody from Novus Biologicals is a rabbit polyclonal antibody to Proteasome 20S alpha 3. This antibody reacts with human, mouse. The Proteasome 20S alpha 3 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Catalog Number: (TS61131-5000)

Supplier:  THERMO FISHER SCIENTIFIC CHEMICALS
Description:   1-Naphtholbenzeine in acetic acid indicator
Catalog Number: (10106-650)

Supplier:  Prosci
Description:   The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function.
Supplier:  THERMO FISHER SCIENTIFIC CHEMICALS
Description:   α,α,α-Trifluoro-p-toluidine 99%

Supplier:  Bioss
Description:   Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.
Catalog Number: (103229-272)

Supplier:  Novus Biologicals
Description:   IL-1 alpha/IL-1F1 Polyclonal Antibody, Host: Goat, Species reactivity: Cotton Rat, Isotype: IgG, Immunogen: E. Coli-derived recombinant cotton rat IL-1 alpha /IL-1F1, synonyms: Hematopoietin-1, IL-1 alpha, IL1, Application: WB, Neut, Size: 100UG

Supplier:  Bioss
Description:   Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Supplier:  Novus Biologicals
Description:   Mouse Monoclonal Integrin alpha 3 Antibody (MM0416-2C39). Tested Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin. Tested Reactivity: Human.

Supplier:  Novus Biologicals
Description:   The Alpha-mannosidase II Antibody (1G9) from Novus Biologicals is a mouse monoclonal antibody to Alpha-mannosidase II. This antibody reacts with human. The Alpha-mannosidase II Antibody (1G9) has been validated for the following applications: Western Blot, ELISA.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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