Methyl+2,4-difluoro-5-methoxybenzoate
Supplier:
AOB CHEM USA
Description:
3-(Benzyloxy)-2-fluoro-4-methoxybenzoic acid ≥97%
Supplier:
AMBEED, INC
Description:
2-Fluoro-6-methoxybenzoic acid, Purity: 97%, CAS number: 137654-21-8, Appearance: Form: Crystal - Powder / Colour: White - Yellow, Storage: Sealed in dry, Room Temperature, Size: 10G
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041716-1G , MDL Number: MFCD02682215
Catalog Number:
(102667-836)
Supplier:
Matrix Scientific
Description:
3-(Azidomethyl)-N-methyl-1,2,4-oxadiazole-5-carboxamide
Supplier:
BeanTown Chemical
Description:
CAS: 872-50-4; EC No: 212-828-1; MDL No: MFCD00003193; RTECS: UY5790000
Liquid; Molecular Formula: C5H9NO; MW: 99.13
Melting Point: -24°; Boiling Point: 202°; Flash point: 91°C (196°F)
Density (g/mL): 1.028; Refractive Index: 1.470
Catalog Number:
(101094-734)
Supplier:
MP Biomedicals
Description:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR.
Methotrexate is used for chemotherapy either alone or in combination with other agents. It is effective for the treatment of a number of cancers including: breast, head and neck, leukemia, lymphoma, lung, osteosarcoma, bladder, and trophoblastic neoplasms. It is also used in treatment of autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It is used to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites. Potent inhibitor of dihydrofolate reductase and agent for antitumor studies. Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also shows immunosuppressive effects in, e.g., rheumatoid arthritis. Methotrexate is an allosteric inhibititor of dihydrofolate reductase (DHFR), the enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. Since tetrahydrolfolate is required for purine and pyrimidine synthesis, methotrexate treatment results in the inhibition of DNA and RNA synthesis.
Supplier:
AMBEED, INC
Description:
1-(((5-(4-Nitrophenyl)furan-2-yl)methylene)amino)imidazolidine-2,4-dione 98%
Supplier:
Adipogen
Description:
LDK378 is potent inhibitor against ALK with IC(50) of 0.2nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
Catalog Number:
(TCA1821-1G)
Supplier:
TCI America
Description:
CAS Number: 22900-11-4
Molecular Formula: C12H21NO9 Molecular Weight: 323.30 Purity/Analysis Method: >95.0% (HPLC) Form: Crystal Flash Point (°C): 113 Specific rotation [a]20/D: -27.5 deg (C=1, H2O) Storage Temperature: <0°C
Supplier:
AOB CHEM USA
Description:
3-Chloro-2-methyl-1,1'-biphenyl ≥97%
Supplier:
AOB CHEM USA
Description:
2-Bromo-4-fluoro-5-methoxybenzoic acid ≥97% research grade
Supplier:
AMBEED, INC
Description:
Biapenem 98%
Catalog Number:
(EM8.03068.0100)
Supplier:
BeanTown Chemical
Description:
CAS: 872-50-4; EC No: 212-828-1; MDL No: MFCD00003193; RTECS: UY5790000
Liquid; Molecular Formula: C5H9NO; MW: 99.13
Melting Point: -24°; Boiling Point: 202°; Flash point: 91°C (196°F)
Density (g/mL): 1.028; Refractive Index: 1.470
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