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Catalog Number:
(75931-152)
Supplier:
Rockland Immunochemical
Description:
Presenilin1 was initially identified a marker of susceptibility to early-onset Alzheimer's disease. In addition to PEN2, nicastrin and APH-1, Presenilin1 forms the gamma-secretase protein complex, a membrane-bound aspartyl protease that can cleave certain proteins at peptide bonds buried within the hydrophobic environment of the lipid bilayer. This cleavage is responsible for a key step in signaling from several cell-surface receptors and is thought to be required for the generation of the neurotoxic amyloid peptides that are central to the pathogenesis of Alzheimer's disease. Like the tumor necrosis factor-alpha-converting enzyme (TACE) and the beta-site cleavage enzyme (BACE) protease families, gamma-secretase will cleave the amyloid precursor protein (APP), but within the intramembrane region of APP, resulting in either the non-toxic p3 (from the alpha and gamma cleavage site) or the toxic Abeta amyloid peptide (from the beta and gamma cleavage site). It is thought that accumulation of the Abeta peptide is the precursor to Alzheimer's disease. Multiple isoforms of presenilin1 are known to exist. This antibody has no cross-reactivity to presenilin2.
Supplier:
Ace Glass
Description:
This apparatus is designed for the U.S.E.P.A
Catalog Number:
(75834-874)
Supplier:
Restek
Description:
Consists of 65 components, those are acenaphthene, acenaphthylene, acetophenone, anthracene, benzanthracene, benzopyrene, benzofluoranthene, benzoperylene, benzofluoranthene, benzyl butyl phthalate, biphenyl, bismethane, bisether, bisphthalate, 4-bromophenyl-phenylether, carbazole, 4-chloroaniline, 4-chloro-3-methylphenol, 2-chloronaphthalene, 2-chlorophenol, 4-chlorophenyl-phenylether, chrysene, dibenzanthracene, dibenzofuran, 3,3'-dichlorobenzidine, 2,4-dichlorophenol, diethylphthalate, 2,4-dimethylphenol, dimethylphthalate, di-n-butylphthalate, 4,6-dinitro-2-methylphenol , 2,4-dinitrophenol, 2,4-dinitrotoluene, 2,6-dinitrotoluene, di-n-octyl phthalate, diphenylamine *,fluoranthene, fluorene, hexachlorobenzene, hexachloro-1,3-butadiene , hexachlorocyclopentadiene, hexachloroethane, indenopyrene, isophorone, 2-methylnaphthalene, 2-methylphenol , 3-methylphenol, 4-methylphenol , naphthalene, 2-nitroaniline, 3-nitroaniline, 4-nitroaniline, nitrobenzene, 2-nitrophenol, 4-nitrophenol, n-nitroso-di-n-propylamine, 2,2'-oxybis, pentachlorophenol, phenanthrene, phenol, pyrene, 1,2,4,5-tetrachlorobenzene, 2,3,4,6-tetrachlorophenol, 2,4,5-trichlorophenol and 2,4,6-trichlorophenol.
Catalog Number:
(SXC11-18)
Supplier:
SPEX CERTIPREP LLC
Description:
Petroleum and LUST Standards
The EPA regulates the monitoring and testing of underground storage tanks (USTs), that were or are used to store petroleum or other hazardous substances, which could impact the environment and human health. Currently, there are over half a million registered underground storage tanks in the US alone. Many tanks installed prior to the mid-80s were composed of steel, which can corrode over time allowing for leakage into the surrounding groundwater and soil. The Hazardous and Solid Waste Amendments to the Resource Conservation and Recovery Act (RCRA), passed in 1984, required the US Environmental Protection Agency (EPA) to develop regulations for the underground storage of motor fuels. The EPA requires owners and operators of USTs to maintain and clean up sites damaged by petroleum contamination. SPEX CertiPrep provides standards designed to meet the testing requirements set up by the EPA and many individual state regulations for LUST and LUFT.
Supplier:
Thermo Scientific Chemicals
Description:
A synthetic intermediate and a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis post serum/potassium deprivation
Catalog Number:
(BDH7923-2)
Catalog Number:
(BDH9272-500G)
Supplier:
Strem Chemicals Inc
Description:
Diethylenetriamine 95
Catalog Number:
(76457-464)
Supplier:
VWR International
Description:
VWR® Carbon Steel Scalpel Blades are made from high quality carbon steel and sharpened to perfection.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041491-1G , MDL Number: MFCD00273468
Catalog Number:
(BDH83635.400)
Supplier:
VWR International
Description:
BDH* n-Propyl Alcohol, Chemical Formula: CH3CH2CH2OH, Melting Point: -126.1, Boiling Point: 97.2, Flash Point: 23 deg C, Formula Weight: 60.10, CAS Number: 71-23-8, Grade: HPLC/Spectro, HiPerSolv CHROMANORM, Class: F, Size: 4L
Catalog Number:
(76520-134)
Supplier:
VWR International
Description:
Includes an extra wire frame shelf made to fit VWR® stainless steel upright units.
Catalog Number:
(MFLX74201-00)
Supplier:
VWR International
Description:
A cost-effective pump for pressure injection and chemical feed applications.
Catalog Number:
(76457-500)
Supplier:
VWR International
Description:
VWR® Sterile Disposable Scalpels are mounted on plastic handles with fluted finger-grips.
Catalog Number:
(98000-214)
Supplier:
VWR International
Description:
Thermometer features stainless steel construction with plastic dial face.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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