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Methyl+3,5-dimethyl-4-propoxybenzoate
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Methyl+3,5-dimethyl-4-propoxybenzoate
Catalog Number:
(80601-362)
Supplier:
MilliporeSigma
Description:
Pravastatin, Sodium Salt, a water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis (Kᵢ = ~1 nM).
Catalog Number:
(101804-748)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 016448-500MG , MDL Number: MFCD06800734
Catalog Number:
(101930-968)
Supplier:
Matrix Scientific
Description:
MF=C13H15N5O MW=257.30 MDL=MFCD19103551 ,500Mg
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 048617-500MG , MDL Number: MFCD12922682
Catalog Number:
(10392-890)
Supplier:
Bioss
Description:
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.
Catalog Number:
(75933-798)
Supplier:
Rockland Immunochemical
Description:
KDM4A or lysine (K)-specific demethylase 4A is a member of the Jumonji domain 2 (JMJD2) family that encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. KDM4A functions in euchromatin to remove histone methylation marks that are associated with active transcription (1). KDM4A also act as a trimethylation-specific demethylase those converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor (2). KDM4A Protein is ideal for investigators involved in Cancer, Cell Cycle, and Inflammation research.
Supplier:
Thermo Scientific Chemicals
Description:
MDL: MFCD00011750
Beilstein Registry No.: 4077708
Catalog Number:
(101913-314)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 057565-500MG , MDL Number: MFCD00457523
Supplier:
TCI America
Description:
CAS Number: 624-78-2
MDL Number: MFCD00009030 Molecular Formula: C3H9N Molecular Weight: 59.11 Purity/Analysis Method: >98.0% (GC) Form: Clear Liquid Boiling point (°C): 35 Flash Point (°C): -34 Specific Gravity (20/20): 0.69 Storage Temperature: 0-10°C
Supplier:
Enzo Life Sciences
Description:
Akt inhibitor
Catalog Number:
(102845-454)
Supplier:
Matrix Scientific
Description:
1-{[(2R,3R)-2-(2,3-Difluorophenyl)-3-methyloxiran-2-yl]methyl}-1H-1,2,3-triazole ≥97%
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 043207-5G , MDL Number: MFCD00215246
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044168-1G , MDL Number: MFCD01568345
Catalog Number:
(101842-138)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 036816-500MG , MDL Number: MFCD07657902
Catalog Number:
(101838-790)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 035001-500MG , MDL Number: MFCD12026581
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 059127-1G , MDL Number: MFCD11052385
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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