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Methyl+3-(benzyloxy)-4,6-dibromopicolinate
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Methyl+3-(benzyloxy)-4,6-dibromopicolinate
Supplier:
Dickies
Description:
Dickies® style 874.
Catalog Number:
(75930-710)
Supplier:
Rockland Immunochemical
Description:
The p53 tumor-suppressor protein can induce apoptosis through transcriptional activation of several genes. One such protein p53AIP was initially identified through direct cloning of p53 binding sequences from human genomic DNA. Its expression is inducible by p53 following p53 phosphorylation on Ser-46, and ectopic expression of p53AIP leads to apoptotic cell death. Both the phosphorylation of p53 and the induction of p53AIP were blocked by inhibiting the expression of p53DINP1 by the introduction of antisense oligonucleotides to p53DINP1, suggesting that the apoptosis associated with p53AIP expression is regulated by p53DINP1. Finally, as adenovirus-mediated introduction of p53AIP has been shown to suppress tumor growth in vivo, it has been suggested that p53AIP gene transfer may become a useful strategy for the treatment of p53-resistant cancers. Three isoforms of p53AIP are known to exist; this antibody will detect all three.
Catalog Number:
(102971-638)
Supplier:
Adipogen
Description:
VASP (vasodilator-stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping proteins. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments and it plays a role in actin-based mobility of Listeria monocytogenes in host cells. It regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. VASP phosphorylation is used to monitor the effect of so-called antiplatelet drugs that reduce platelet reactivity and are used to prevent stent thrombosis, strokes and heart attacks in patients. Phosphorylation of VASP at Ser157 causes a mobility shift in SDS gel electrophoresis from 46 to 50kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity.
Catalog Number:
(10296-612)
Supplier:
Bioss
Description:
The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46% sequence identity with GGA1 and 38% with GGA2.
Catalog Number:
(76070-230)
Supplier:
Prosci
Description:
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50 For FACS starting dilution is: 1:10~50
Catalog Number:
(103267-792)
Supplier:
Novus Biologicals
Description:
The C16orf46 Antibody from Novus Biologicals is a rabbit polyclonal antibody to C16orf46. This antibody reacts with human. The C16orf46 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(103327-306)
Supplier:
Novus Biologicals
Description:
The GMDS Antibody from Novus Biologicals is a rabbit polyclonal antibody to GMDS. This antibody reacts with human, mouse. The GMDS Antibody has been validated for the following applications: Western Blot.
Supplier:
MP Biomedicals
Description:
AlbumiNZâ„¢ Low Fatty Acid BSA is chromatographically purified from New Zealand-sourced bovine plasma in an ISO quality system assuring complete traceability and consistent high quality. This albumin has very low endotoxin and low free fatty acids, is tested for the absence of viruses according to 9CFR and has the highest possible biosafety level.
Catalog Number:
(76008-800)
Supplier:
Prosci
Description:
MESP1 is a transcription factor. It plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways (By similarity).
Catalog Number:
(10296-604)
Supplier:
Bioss
Description:
The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46% sequence identity with GGA1 and 38% with GGA2.
Catalog Number:
(103280-386)
Supplier:
Novus Biologicals
Description:
The C7orf46 Antibody from Novus Biologicals is a rabbit polyclonal antibody to C7orf46. This antibody reacts with human. The C7orf46 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Supplier:
Adipogen
Description:
Systemic fungicide developed for the control of rice diseases that exhibits strong antifungal activity against many plant-pathogenic fungi. Antifungal activity does not affect the synthesis of RNA, DNA, protein, cell walls, or lipid components. Inhibits mycelial growth, but does not inhibit spore germination until a germ tube had formed. No effect of ferimzone was observed on the cell wall architecture of mycelia. Ferimzone causes leakage of some electrolytes from mycelia, which suggests that it affects or disrupts membrane function. Compound can be used as analytical reference material.
Catalog Number:
(103266-738)
Supplier:
Novus Biologicals
Description:
The CCDC46 Antibody from Novus Biologicals is a rabbit polyclonal antibody to CCDC46. This antibody reacts with human. The CCDC46 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(103267-794)
Supplier:
Novus Biologicals
Description:
The C16orf46 Antibody from Novus Biologicals is a rabbit polyclonal antibody to C16orf46. This antibody reacts with human. The C16orf46 Antibody has been validated for the following applications: Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number:
(75794-126)
Supplier:
Prosci
Description:
Meteorin-like (cometin; subfatin) is a potent new neurotrophic factor promoting neurite outgrowth from dorsal root ganglion cells. Meteorin-like is also a novel adipokine expressed by adipose tissue being downregulated upon caloric restriction. Meteorin-like is secreted by muscles during exercise and converts white adipose cells into brown fat tissue.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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