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(1H-Benzoimidazol-2-yl)methanol
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(1H-Benzoimidazol-2-yl)methanol
Catalog Number:
(10427-202)
Supplier:
Bioss
Description:
Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.
Catalog Number:
(10801-184)
Supplier:
Rockland Immunochemical
Description:
Donkey IgG (HandL)Polyclonal antibody, Host: Rabbit, Species: Donkey, Format: IgG, Conjugation: HRP, Concentration: 10.0 mg/mL by UV absorbance at 280 nm, Application: Elisa, WB, Ihc, 20mg
Supplier:
R&D Systems
Description:
NTB-A/SLAMF6/CD352, Monoclonal Antibody, Clone: 292811, Host: Mouse, Isotype: IgG2a, Species reactivity: Human, Format:Phycoerythrin, Immunogen: Mouse myeloma cell line NS0-derived recombinant human NTB-A/SLAMF6, Synonym: Ly108, Application: FC, Size: 25 test
Catalog Number:
(BJ09752-100ML)
Supplier:
Honeywell Research Chemicals
Description:
Formic acid : Triethylamine 1:1 solution, CAS Number: 585-29-5, MF: (CH3CH2)3NH+ HCOO-, Molecular Weight: 147.22 g/mol, 2M : 2M solution for HPLC, concentrate in H2O, Analytical, Synonyms: Triethylammonium formate solution; TEAF, Size: 100ML
Catalog Number:
(10290-174)
Supplier:
Bioss
Description:
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.
Supplier:
INTACT GENOMICS, INC MS
Description:
DirectPlate™ TG1 phage display chemically competent <i>Escherichia coli</i> cells are a perfect choice for researchers looking to simplify their transformation workflow by eliminating heat shock, lengthy incubations, and time-consuming outgrowth procedures. Simply mix and directly plate!
Supplier:
R&D Systems
Description:
MICB Monoclonal antibody, Host: Mouse, Clone: 236511, Isotype: IgG2b, Species reactivity: human, Format: [Alexa Fluor 700], Immunogen: Mouse myeloma cell line NS0-derived recombinant human MICB Ala23-Gly298, Synonyms: MIC-B, Application: flow, Size: 100 tests
Catalog Number:
(10332-344)
Supplier:
Bioss
Description:
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
Catalog Number:
(10388-716)
Supplier:
Bioss
Description:
Signaling adapter that controls various cellular protrusions by regulating actin cytoskeleton dynamics and architecture. Depending on its association with other signal transducers, can regulate different processes. Together with SOS1 and ABI1, forms a trimeric complex that participates in transduction of signals from Ras to Rac by activating the Rac-specific guanine nucleotide exchange factor (GEF) activity. Acts as a direct regulator of actin dynamics by binding actin filaments and has both barbed-end actin filament capping and actin bundling activities depending on the context. Displays barbed-end actin capping activity when associated with ABI1, thereby regulating actin-based motility process: capping activity is auto-inhibited and inhibition is relieved upon ABI1 interaction. Also shows actin bundling activity when associated with BAIAP2, enhancing BAIAP2-dependent membrane extensions and promoting filopodial protrusions. Involved in the regulation of processes such as axonal filopodia growth, stereocilia length, dendritic cell migration and cancer cell migration and invasion. Acts as a regulator of axonal filopodia formation in neurons: in the absence of neurotrophic factors, negatively regulates axonal filopodia formation via actin-capping activity. In contrast, it is phosphorylated in the presence of BDNF leading to inhibition of its actin-capping activity and stimulation of filopodia formation. Component of a complex with DFNB31 and MYO15A that localizes at stereocilia tips and is required for elongation of the stereocilia actin core. Indirectly involved in cell cycle progression; its degradation following ubiquitination being required during G2 phase to promote cell shape changes.
Catalog Number:
(10261-452)
Supplier:
Bioss
Description:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyzes the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist.
Catalog Number:
(10261-458)
Supplier:
Bioss
Description:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane, known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through the formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine to a glutaminyl residue, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. TGase6 (transglutaminase 6), also known as TGM6, TGY or TGM3L, is a 706 amino acid protein that catalyzes the cross-linking of proteins and the conjugation of proteins to polyamines. As a result of alternative splicing, two TGase6 isoforms exist.
Catalog Number:
(10264-554)
Supplier:
Bioss
Description:
GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain, heart and muscle, and weakly expressed in small intestine, colon, liver, placenta and lung. GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation. GEFT is an important regulator of processes involved in axon and dendrite formation. Involved in skeletal myogenesis, GEFT seems to be an exchange factor primarily for Rac 1 in neurons. Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain.
Supplier:
New England Biolabs (NEB)
Description:
Catalyzes the formation of a phosphodiester bond between juxtaposed 5'-phosphate and 3'-hydroxyl termini in duplex DNA containing cohesive ends.
Catalog Number:
(76498-148)
Supplier:
Berkshire
Description:
SatPax® wipers provide a convenient combination of solvent and wiper that improves the cleaning process.It resolves safety issues associated with storage, mixing, and dispensing of solvents.
Catalog Number:
(10802-462)
Supplier:
Rockland Immunochemical
Description:
IGG, Polyclonal Antibody, Conjugate: FITC, Host: Rabbit, Target Species: Donkey, Format: IgG, Specificity: purified from monospecific antiserum, Immunogen: Donkey IgG whole molecule, Isotype: IgG, Application: FLISA, IF, Size: 20MG
Catalog Number:
(10802-306)
Supplier:
Rockland Immunochemical
Description:
CHICKEN IGG F(AB)2, Polyclonal Antibody, Conjugate: FITC, Host: Rabbit, Target Species: Chicken, Format: IgG, Immunogen: Chicken IgG F(ab)2 fragment, Isotype: IgG, Application: FLISA, IF Microscopy, Flow cytometry, Size: 20MG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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