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Methyl-2-aminothiazole-5-carboxylate
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Methyl-2-aminothiazole-5-carboxylate
Catalog Number:
(76078-512)
Supplier:
Bioss
Description:
Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage: recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection. Involved in maintenance of DNA methylation via its interaction with UHRF1 and DNMT1: acts by mediating deubiquitination of UHRF1 and DNMT1, preventing their degradation and promoting DNA methylation by DNMT1. Exhibits a preference towards 'Lys-48'-linked ubiquitin chains. Increases regulatory T-cells (Treg) suppressive capacity by deubiquitinating and stabilizing the transcription factor FOXP3 which is crucial for Treg cell function (PubMed:23973222).
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 037605-25G , MDL Number: MFCD01076207
Supplier:
AMBEED, INC
Description:
tert-Butyl 4-(4-aminophenyl)piperidine-1-carboxylate, Purity: 97%, CAS number: 170011-57-1, Appearance: Powder or crystals, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 10G
Supplier:
AMBEED, INC
Description:
tert-Butyl 4-carbamoylpiperidine-1-carboxylate, Purity: 97%, CAS Number: 91419-48-6, Appearance: Form: Crystal - Powder / Colour: White - Almost white, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 500G
Supplier:
TCI America
Description:
Tert-Butyl 6-Oxa-3-Azabicyclo[3.1.0]Hexane-3-Carboxylate, Purity: >95.0%(GC), Cas no: 114214-49-2, Molecular formula : C9H15NO3, Molecular weight : 185.22, Synonyms: 1-Boc-3,4-epoxypyrrolidine, Size: 1G
Supplier:
AMBEED, INC
Description:
N-Boc-Azetidine-3-carboxylic acid, Purity: 97%, CAS Number: 142253-55-2, Appearance: Form: Crystal - Powder/Colour: White - Very pale yellow, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 25g
Catalog Number:
(76219-370)
Supplier:
TCI America
Description:
(4S,5R)-3-(tert-Butoxycarbonyl)-2,2-dimethyl-4-phenyl-1,3-oxazolidine-5-carboxylic Acid, Purity: >98.0%(GC)(T), CAS: 143527-70-2, Molecular Formula: C17H23NO5, Molecular Weight: 321.37, Size: 200MG
Catalog Number:
(100295-142)
Supplier:
Indofine Chemical Company
Description:
Rare Organics & BioChemicals 144222-22-0 1gm 214.3 Room temperature. 95%.
Supplier:
AMBEED, INC
Description:
(S)-Ethyl-N-boc-pyroglutamate 97%
Supplier:
Thermo Scientific Chemicals
Description:
Ethyl (S)-1-Boc-5-oxopyrrolidine-2-carboxylate, 98%
Supplier:
AMBEED, INC
Description:
3-Methylpicolinic acid, Purity: 97%, CAS Number: 4021-07-2, Appearance: Form: Crystal - Powder / Colour: White - Almost white, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 5g
Supplier:
BeanTown Chemical
Description:
CAS: 144978-12-1; MDL No: MFCD07778090
Solid; Molecular Formula: C12H19NO5 ; MW: 257.28
Supplier:
TCI America
Description:
4-(Aminomethyl)-1-tert-butoxycarbonylpiperidine, Purity: >98.0%(GC)(T), Cas number: 144222-22-0, Molecular Formula: C11H22N2O2, Molecular Weight: 214.31, Appearance: Clear liquid, Synonyms: 4-(Aminomethyl)-1-Boc-piperidine, Size: 1G
Supplier:
AMBEED, INC
Description:
1-Boc-4-(Aminomethyl)piperidine, Purity: 97%, CAS Number: 144222-22-0, Appearance: Colorless to pale-yellow liquid or solid, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 100g
Catalog Number:
(101842-804)
Supplier:
Matrix Scientific
Description:
Ethyl-6-hydroxypyridine-2-carboxylate
Supplier:
Matrix Scientific
Description:
Ethyl pyrrole-2-carboxylate 97
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