(2-Fluoro-5-methoxyphenyl)(thiomorpholino)methanone
Catalog Number:
(103008-176)
Supplier:
Anaspec Inc
Description:
This 1-21 amino acid histone H3 peptide has a trimethylated lysine at position 9. This form of histone methylation is characterized as being enriched around transcription start sites. It has been observed that certain family members of the JMJ enzyme (Jumonji C domain-containing oxygenases) that play a role in regulating the methylation status of histone H3 lysine residues exhibits selectivity towards this peptide.
Sequence:ARTKQTAR-K(Me3)-STGGKAPRKQLA MW:2296.6 Da % peak area by HPLC:95 Storage condition:-20° C
Catalog Number:
(10261-422)
Supplier:
Bioss
Description:
ESET is a nuclear protein belonging to the histone-lysine methyltransferase family and to the Suvar3-9 subfamily. It is a highly conserved protein of 150 amino acids that has been implicated in chromatin structure modulation. ESET is excluded from cell nucleoli and areas of condensed chromatin and can associate with the nonpericentromeric regions of chromatin. The gene encoding for this protein, SETDB1, maps to chromosome 1q21. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts as a tag for epigenetic transcriptional repression by rounding up HP1 proteins to methylated histones. ESET is widely expressed with highest levels found in testis.
Catalog Number:
(102845-108)
Supplier:
Matrix Scientific
Description:
4-Chloro-5-methoxy-2-methylpyridazin-3(2H)-one ≥97%
Catalog Number:
(101928-804)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 065002-500MG , MDL Number: MFCD00006859
Supplier:
AMBEED, INC
Description:
2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one, Purity: 98%, CAS Number: 955365-80-7, Appearance: White to Yellow to yellow-green powder or crystals, Storage: Sealed in dry, Store in freezer, under -20C, Size: 1MG
Supplier:
Enzo Life Sciences
Description:
Duvelisib is an orally bioavailable and highly selective inhibitor of PI3K-δ and PI3K-γ with IC50 values of 0.36 nM and 19.6 nM, respectively.
Catalog Number:
(TCP1905-10G)
Supplier:
TCI America
Description:
CAS Number: 36322-90-4
MDL Number: MFCD00057317 Molecular Formula: C15H13N3O4S Molecular Weight: 331.35 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Color: White Melting point (°C): 201 Lambda max.: 358 nm (H2O)Storage Temperature: 0-10°C
Catalog Number:
(TCH1459-200MG)
Supplier:
TCI America
Description:
(1H,1H,2H,2H-Heptadecafluorodecyl)phosphonic Acid, Purity: >96.0%(HPLC)(T), CAS Number: 80220-63-9, MF: C10H6F17O3P, MW: 528.1, Synonym: (1H,1H,2H,2H-Perfluorodecyl)phosphonic Acid, Physical state: Solid, Form: Crystal - Powder, Size: 200MG
Supplier:
ALADDIN SCIENTIFIC
Description:
Alfacalcidol ≥97%
Catalog Number:
(101836-300)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 033753-500MG , MDL Number: MFCD01463444
Supplier:
Matrix Scientific
Description:
MF=C10H12CLNO2 MW=213.67 CAS=77497-95-1 MDL=MFCD00800357 10G
Catalog Number:
(101850-986)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041227-500MG , MDL Number: MFCD09998373
Catalog Number:
(10075-374)
Supplier:
Prosci
Description:
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s disease, epilepsy and ischemic neuronal cell death. Increased membrane surface expression of the NR1 subunit of the receptor has been associated with synaptic plasticity. There are a number of different splice variants of the NR1. Differential splicing of three exons in the NR1 subunit generates up to eight NR1 splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2'). Considerable attention has been focused on the distribution and expression of these splice variants that may affect the functional properties and regulation of the NMDAR.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Potassium oxonate 97.5%
Supplier:
ALADDIN SCIENTIFIC
Description:
Aprepitant is a potent and selective neurokinin-1 receptor antagonist
Catalog Number:
(103508-400)
Supplier:
Acros Organics
Description:
Adenosine 5'-triphosphate, Cas number: 34369-07-8, Purity: 98%, Molecular Weight: 551.14, Molecular Formula: C10 H14 N5 Na2 O13 P3. X H2 O, Form: Powder, Solid, Color: White, Synonyms: ATP, disodium salt hydrate, Size: 10G
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