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Supplier:
AMBEED, INC
Description:
Methyl 1-aminocyclopentanecarboxylate hydrochloride, Purity: 95%, CAS Number: 60421-23-0, Appearance: Form: Crystal - Powder / Colour: White - Almost white, Storage: Inert atmosphere, Room Temperature, Size: 1G
Supplier:
AMBEED, INC
Description:
3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic Acid, Purity: 99%, CAS Number: 68399-81-5, Appearance: Form: Crystal - PowderColour: White - Almost white, Storage: Keep in dark place, Inert atmosphere, Room temperature, Size: 100G
Catalog Number:
(100504-948)
Supplier:
Electron Microscopy Sciences
Description:
A technique producing an electron dense osmiophilic polymer when Lucifer yellow is injected into cells. Lucifer yellow also can be viewed in living cells as a dye marker and is more sensitive than any other dye.
Supplier:
AMBEED, INC
Description:
3,5-Di-tert-butylaniline, Purity: 95%, CAS Number: 2380-36-1, Appearance: White to Yellow to Orange Solid or Semi-solid or liquid, Storage: Keep in dark place, Sealed in dry, Room Temperature, Size: 5g
Supplier:
Adipogen
Description:
Orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathways, with potential antineoplastic activity. Specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.
Catalog Number:
(76483-482)
Supplier:
AAT BIOQUEST INC
Description:
CytoTraceâ„¢ Orange CMTMR is chemically same to CellTrackerâ„¢ Orange CMTMR.
Catalog Number:
(101847-750)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 039570-500MG , MDL Number: MFCD12028030
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041638-100MG , MDL Number: MFCD02682499
Catalog Number:
(89416-032)
Supplier:
Prosci
Description:
IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Supplier:
AMBEED, INC
Description:
2-(2-((3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl)-1H-indole ≥99%
Catalog Number:
(101928-656)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 064928-500MG , MDL Number: MFCD00665175
Catalog Number:
(75791-954)
Supplier:
Prosci
Description:
Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 045149-5G , MDL Number: MFCD05663794
Supplier:
AMBEED, INC
Description:
2-Aminobenzhydrol 97%
Catalog Number:
(10263-186)
Supplier:
Bioss
Description:
AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (1–3). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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