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3-(4-Fluorophenyl)-5-methoxypyridine
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3-(4-Fluorophenyl)-5-methoxypyridine
Catalog Number:
(10297-240)
Supplier:
Bioss
Description:
The glycine cleavage system is comprised of AMT (known as Protein T), GCSH (known as Protein H), DLD (known as Protein L) and GLDC (known as Protein P), all of which work together to catalyze the cleavage and degradation of glycine. GLDC (glycine dehydrogenase ), also known as GCE, GCSP (glycine cleavage system P protein) or HYGN1, is a 1,020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family. GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T. GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor. Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.
Catalog Number:
(10268-690)
Supplier:
Bioss
Description:
Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
Catalog Number:
(100504-276)
Supplier:
Electron Microscopy Sciences
Description:
Na2CO3 F.W. 105.99 CAS 497-19-8
Catalog Number:
(RL205-4150)
Supplier:
Rockland Immunochemical
Description:
Anti-Goat IgG (H&L) (Goat) Antibody Agarose Conjugated is applicable to purification of Goat IgG from sample solution.
Catalog Number:
(102995-450)
Supplier:
Cell Sciences
Description:
Flow Cytometry: Use 10 µl to label 10E6 cells or 100 µl of whole blood.
Catalog Number:
(RL610-4921)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG F(ab')2 Reacts with Mouse
Catalog Number:
(RL602-4903)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG F(c) Reacts with Cat (Feline)
Catalog Number:
(76075-986)
Supplier:
Prosci
Description:
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50
Catalog Number:
(RL604-1203)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgG F(c) Reacts with Dog (Canine)
Catalog Number:
(RL610-702-002)
Supplier:
Rockland Immunochemical
Description:
Secondary Donkey Anti-IgG (H&L) Reacts with Mouse
Catalog Number:
(RL606-106-129)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgG (H&L) Reacts with Guinea Pig
Catalog Number:
(RL710-109-130)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgG IgA IgM Reacts with Mouse
Catalog Number:
(RL603-100-126)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgG F(ab')2 Reacts with Chicken
Catalog Number:
(10302-240)
Supplier:
Bioss
Description:
Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).
Catalog Number:
(14217-850)
Supplier:
Thermo Scientific
Description:
Orion™ AQUAfast™ Auto-Test Ampoule Reagents can be used with the Orion™ AQUAfast™ AQ4000 colorimeter to simplify sample preparation and tests.
Catalog Number:
(RL707-409-002)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG (H&L) Reacts with Hamster
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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