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N(α)-Boc-D-tryptophan


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Catalog Number: (75793-540)

Supplier:  Prosci
Description:   IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
Supplier:  ALADDIN SCIENTIFIC
Description:   Application:Antalarmin hydrochloride has been used:to study its effect on stress-induced tryptophan hydroxylase 2 activityto study the anxiogenic effects of corticotropin-releasing factor 1 (CRF1) activationto analyze the therapeutic effect of blocking corticotrophin-releasing hormone (CRH) signaling in treating social stress-induced depressionAntalarmin hydrochloride is a non-peptide CRF1 corticotropin-releasing factor receptor antagonist.
New Product
Supplier:  Adipogen
Description:   7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. It is a photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine beta-synthase (CBS) inhibitors and activators.

Supplier:  MilliporeSigma
MSDS SDS
Supplier:  Bioss
Description:   GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.

Supplier:  Bioss
Description:   GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Catalog Number: (10231-962)

Supplier:  Bioss
Description:   GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
Catalog Number: (75789-236)

Supplier:  Prosci
Description:   There exists two types of tryptophanyl tRNA synthetases, the cytoplasmic form called WARS, the mitochondrial form called WARS2. WARS catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. WARS regulates ERK, Akt, eNOS activation pathway, which are related with angiogenesis, cytoskelatal reorganization and shear stess-reponsive gene expression.
Catalog Number: (103308-818)

Supplier:  Novus Biologicals
Description:   The PWP2H Antibody from Novus Biologicals is a mouse polyclonal antibody to PWP2H. This antibody reacts with human. The PWP2H Antibody has been validated for the following applications: Western Blot, Immunocytochemistry / Immunofluorescence.
Supplier:  G-Biosciences
Description:   Immobilized Metal Ion Affinity Chromatography (IMAC), developed by Porath (1975), is based on the interaction of certain protein residues (histidines, cysteines, and to some extent tryptophans) with cations of transition metals
Supplier:  INTACT GENOMICS, INC MS
Description:   Chemically competent DL39 (DE3) <i>E. coli</i> cells are specific for transformation and protein expression in order to uniformly and specifically label e.g. phenylalanine or leucine residues. DL39 (DE3) can also be used to reduce NMR cross-labeling via. transaminase activity for valine, leucine, isoleucine, aspartate, phenylalanine, tyrosine and tryptophan residues.
Supplier:  ANTIBODIES.COM LLC
Description:   Rabbit polyclonal antibody to TPH2 for WB and ELISA with samples derived from Human, Mouse and Rat.
Catalog Number: (102514-462)

Supplier:  Adipogen
Description:   IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
Catalog Number: (75793-322)

Supplier:  Prosci
Description:   IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
Catalog Number: (102514-788)

Supplier:  Adipogen
Description:   IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
Small Business Enterprise
Supplier:  MP Biomedicals
Description:   Nisin is a polypeptide (34 residues) antibiotic structurally similar to subtilin but containing no tryptophan; a member of the lantibiotic family. Reduces the thermal resistance of bacterial spores in milk-based beverages.The C-terminus of nisin is responsible for the initial interaction of nisin, binding to the target membrane. Active against Gram-positive bacteria at the cytoplasmic membrane.
MSDS SDS
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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