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N-(3-Acetyl-4-hydroxyphenyl)butyramide


7,925  results were found

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Supplier:  Bioss
Description:   HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.

Supplier:  TCI America
Description:   CAS Number: 119851-28-4
MDL Number: MFCD00140226
Molecular Formula: C14H10Cl2O2
Molecular Weight: 281.13
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 58
MSDS SDS
Supplier:  LGC STANDARDS
Description:   Bis(2-isopropylphenyl) Phenyl Phosphate, TRC, LGC Standards
New Product
Supplier:  Prosci
Description:   TIP60 is the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex is required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. TIP60 directly acetylates and activates ataxia-telangiectasia mutated (ATM). In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.
Supplier:  Bioss
Description:   This enzyme condenses acetyl CoA with acetoacetyl CoA to form HMG CoA, which is the substrate for HMG CoA reductase.

Supplier:  Genetex
Description:   Chromatin is a highly specialized structure composed of tightly compacted chromosomal DNA. Gene expression within the nucleus is controlled, in part, by a host of protein complexes which continuously pack and unpack the chromosomal DNA. One of the known mechanisms of this packing and unpacking process involves the acetylation and deacetylation of the histone proteins comprising the nucleosomal core. Acetylated histone proteins confer accessibility of the DNA template to the transcriptional machinery for expression. Histone deacetylases (HDACs) are chromatin remodeling factors that deacetylate histone proteins and thus, may act as transcriptional repressors. HDACs are classified by their sequence homology to the yeast HDACs and there are currently 2 classes. Class I proteins are related to Rpd3 and members of class II resemble Hda1p.
Catalog Number: (89359-238)

Supplier:  Genetex
Description:   Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fibre is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. Covalent modifications of the canonical core histones, including acetylation, phosphorylation, methylation, and monoubiquitination, are used to mark nucleosomes to create chromatin domains with a range of functions. The information encoded by the modifications can contribute to the formation and/or maintenance of transcriptionally active and inactive chromatin in response to various signalling pathways. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones. Phosphorylation of histone H3, referred to as the nucleosomal response, is localized to a small fraction of highly acetylated H3 and occurs primarily in response to mitogenic and stress stimuli.2, 3, 9-12 Phosphorylation of histone H3 on S10 is tightly correlated with chromosome condensation during both mitosis and meiosis. Phosphorylation at this site is also directly correlated with the induction of immediate-early genes such as c-jun, c-fos, and c-myc.
Catalog Number: (103009-012)

Supplier:  Anaspec Inc
Description:   This peptide represents amino acid residues 5-23 of histone H3 and can be used as a substrate for histone acetyl-transferase (HAT) assays.
Sequence:QTARKSTGGKAPRKQLASK
MW:2013.3 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier:  Bioss
Description:   The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Catalog Number: (AAH33332-ME)

Supplier:  Thermo Scientific Chemicals
Description:   500mg CAS: 55804-67-6, MDL: MFCD00051336
MSDS SDS

Supplier:  BIOASSAY SYSTEMS
Description:   Stabilized 10-Acetyl-3,7-dihydroxyphenoxazine (also called Ampliflu Red) liquid substrate reagent for HRP detection.
Supplier:  Boster Biological Technology
Description:   Choline Acetyltransferase Polyclonal Antibody, Host: Rabbit, Reactivity: Mouse, Rat, Immunogen: E.coli-derived rat Choline Acetyltransferase/Chat recombinant protein, Alternative Names: Choline Acetyltransferase/ChAT, acetyl CoA: choline O-acetyltransferase, CHAT, CHOACTase, Size: 100ug/vial
Supplier:  AMBEED, INC
Description:   21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]triene-3,20-dione maleate salt ≥97%
New Product
Supplier:  MilliporeSigma
Description:   Endo-β-Galactosidase, Bacteroides fragilis, Recombinant, E. coli, hydrolyzes internal β-galactosidic linkages of oligosaccharides in poly-N-acetyl-lactosamine structures.
Supplier:  LGC STANDARDS
Description:   1,2-Dioleoyl-rac-glycerol (10 mg/mL in Methyl Acetate), TRC, LGC Standards
New Product

Supplier:  Matrix Scientific
Description:   Matrix Scientific Part Number: 047519-1G , MDL Number: MFCD09864821
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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