2-Amino-N-(sec-butyl)acetamide+hydrochloride
Catalog Number:
(10402-894)
Supplier:
Bioss
Description:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
Catalog Number:
(10402-890)
Supplier:
Bioss
Description:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Tributyltin trifluoromethanesulfonate 96%
Supplier:
BeanTown Chemical
Description:
CAS: 434-45-7; EC No: 207-103-1; MDL No: MFCD00000420
UN No: UN1224; Haz Class: 3; Packing Group: III
Liquid; Molecular Formula: C8H5F3O; MW: 174.12
Boiling Point: 165-166°; Flash point: 41°C (106°F)
Density (g/mL): 1.24; Refractive Index: 1.458
Catalog Number:
(10451-208)
Supplier:
Bioss
Description:
This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Catalog Number:
(76080-284)
Supplier:
Bioss
Description:
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Supplier:
BeanTown Chemical
Description:
CAS: 14165-55-0; EC No: 238-007-8; MDL No: MFCD00015121
UN No: UN1993; Haz Class: 3; Packing Group: III
Liquid; Linear Formula: Ge(OCH2CH3)4; Molecular Formula: C8H20GeO4 ; MW: 252.84
Flash point: 48°C (118°F)
Density (g/mL): 1.14 ; Refractive Index: 1.407
Moisture Sensitive
Supplier:
BeanTown Chemical
Description:
CAS: 70-34-8; EC No: 200-734-3; MDL No: MFCD00007056; RTECS: CZ7800000
UN No: UN2811; Haz Class: 6.1; Packing Group: III
Solid; Molecular Formula: C6H3FN2O4; MW: 186.10
Melting Point: 25-27°; Boiling Point: 178°/25 mmHg; Flash point: 164°C (327°F)
Density (g/mL): 1.482; Refractive Index: 1.569
Catalog Number:
(10338-002)
Supplier:
Bioss
Description:
L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Catalog Number:
(10274-212)
Supplier:
Bioss
Description:
LRFN1 is a 771 amino acid single-pass type I membrane protein that belongs to the LRFN family. Containing a fibronectin type-III domain, an Ig-like (immunoglobulin-like) domain, a LRRCT domain, a LRRNT domain and seven LRR (leucine-rich) repeats, LRFN1 is thought to promote neurite outgrowth in hippocampal neurons and is involved in the regulation and maintenance of excitatory synapses. LRFN1 forms heteromeric complexes with LRFN2, LRFN3, LFRN4 and LFRN5, but does not have the ability to form homomeric complexes across cell junctions of adjacent cells like other LRFN family members. The PDZ-binding motif of LRFN1 is required for neurite outgrowth promotion and for SAP 97-, NE-dlg- and PSD-95-binding. LRFN1 is encoded by a gene located on human chromosome 19q13.2 and mouse chromosome 7 A3.
Supplier:
APOLLO SCIENTIFIC
Description:
Remainder non-aromatic trialkyl and tetraalkyltins.
Catalog Number:
(10266-080)
Supplier:
Bioss
Description:
The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
Catalog Number:
(10429-276)
Supplier:
Bioss
Description:
Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1.
Supplier:
BeanTown Chemical
Description:
CAS: 59-52-9; EC No: 200-433-7; MDL No: MFCD00004864; RTECS: UB2625000
UN No: UN2810; Haz Class: 6.1; Packing Group: III
Liquid; Linear Formula: HOCH2CH(SH)CH2SH; Molecular Formula: C3H8OS2; MW: 124.23
Boiling Point: 120°/15 mmHg; Flash point: 112°C (234°F)
Density (g/mL): 1.239
Air Sensitive
Catalog Number:
(10071-920)
Supplier:
Prosci
Description:
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Catalog Number:
(75933-050)
Supplier:
Rockland Immunochemical
Description:
Human transferrin is encoded by the TF gene and is an iron-binding blood plasma glycoprotein that controls the level of free iron in biological fluids. Human transferrin binds iron very tightly but reversibly. Human transferrin is the most important iron pool in mammals. Human transferrin has a molecular weight of around 80 kDa and contains 2 specific high-affinity Fe(III) binding sites. The affinity of Human transferrin for Fe(III) is extremely high but decreases progressively with decreasing pH below neutrality. Human Transferrin also plays a role in the immune system, creating environments low in iron for which many pathogenic bacteria are unable to thrive.
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