N-Benzylpiperidine-4-carboxamide+hydrochloride
Catalog Number:
(102538-368)
Supplier:
Matrix Scientific
Description:
MF=C18H14CLNO3 MW=327.77 CAS=137-52-0 MDL=MFCD00051171 5G
Catalog Number:
(TCP1382-1G)
Supplier:
TCI America
Description:
CAS Number: 7531-52-4
MDL Number: MFCD00005253 Molecular Formula: C5H10N2O Molecular Weight: 114.15 Purity/Analysis Method: >97.0% (T) Form: Crystal Color: White Melting point (°C): 99 Specific rotation [a]20/D: -106 deg (C=2, EtOH)
Supplier:
Adipogen
Description:
Orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathways, with potential antineoplastic activity. Specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.
Supplier:
Bachem Americas
Description:
LHRH is also called Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF).
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044469-5G , MDL Number: MFCD00232083
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 044470-1G , MDL Number: MFCD01935966
Supplier:
ALADDIN SCIENTIFIC
Description:
tert-Butyl-4-amino-4-carbamoylpiperidine-1-carboxylate ≥97%
Supplier:
AMBEED, INC
Description:
(Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine, Purity: 98+%, CAS Number: 1204669-58-8, Appearance: White to Yellow Solid, Storage: Sealed in dry, 2-8 C, Size: 5mg
Supplier:
Anaspec Inc
Description:
Although FITC reagents have been more often used to prepare fluoresceinated bioconjugates, the low stability of FITC bioconjugates makes some researchers use amine-reactive succinimidyl esters of carboxyfluorescein (commonly called FAM) in bioconjugations. FAM reagents give carboxamides that are more resistant to hydrolysis. We have shown that FAM reagents require less stringent reaction conditions and give better conjugation yields, and the resulted conjugates have superior stability. We noted that FITC labeled peptides tend to deteriorate more quickly than the corresponding FAM conjugates.
Supplier:
TCI America
Description:
CAS Number: 10366-35-5
MDL Number: MFCD00006237 Molecular Formula: C6H5ClN2O Molecular Weight: 156.57 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 164
Supplier:
MP Biomedicals
Description:
Ribavarin is an antiviral compound reported to be active against RSV, HIV, HCV and other infectious agents. Its metabolite, ribavirin 5'-phosphate, inhibits inosine monophosphate dehydrogenase (IMP). It is also an analog of the imidazole nucleotide intermediates in purine nucleotide biosynthesis.
Ribavirin is active against a number of DNA and RNA viruses. It is a member of the nucleoside antimetabolite drugs that interfere with duplication of viral genetic material. Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase, but many other mechanisms of action are also supported with experimental evidence. Antiviral agent whose metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase. Used to inhibit purine (GTP pools) biosynthesis at the level of inosine monophosphate (IMP) dehydrogenase and as a precursor to the di- and tri-phosphates which inhibit viral RNA-dependent RNA polymerases. Store at +4 °C.
Supplier:
TCI America
Description:
CAS Number: 75885-58-4
MDL Number: MFCD00216614 Molecular Formula: C6H11NO Molecular Weight: 113.16 Purity/Analysis Method: >98.0% (GC) Form: Crystal Melting point (°C): 136 Specific rotation [a]20/D: 83 deg (C=1, MeOH)
Supplier:
Adipogen
Description:
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells with IC(50) values of 20 and 45nM, respectively. SAR131675 dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD, with an IC(50) of about 20nM. SAR131675 was found to be highly selective for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. However, it was moderately active on VEGFR-2 with a VEGFR-3/VEGFR-2 ratio of about 10. SAR131675 had no antiproliferative activity on a panel of 30 tumors and primary cells, further showing its high specificity and indicating that SAR131675 is not a cytotoxic or cytostatic agent.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 043818-1G , MDL Number: MFCD00664740
Supplier:
TCI America
Description:
CAS Number: 284462-37-9
MDL Number: MFCD08692047 Molecular Formula: C13H13N3O2 Molecular Weight: 243.27 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 118
Supplier:
AMBEED, INC
Description:
BLU-667 (Pralsetinib) 99%
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