Pentafluorophenyl+isothiocyanate
Catalog Number:
(10407-246)
Supplier:
Bioss
Description:
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
Catalog Number:
(10408-046)
Supplier:
Bioss
Description:
Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.
Catalog Number:
(10471-178)
Supplier:
Bioss
Description:
Microtubules, polymers of alpha and beta tubulin subunits,form the mitotic spindle of a dividing cell and help to organizemembranous organelles during interphase. Katanin is a heterodimerthat consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDaaccessory protein (p80 subunit B 1). The p60 subunit acts to severand disassemble microtubules, while the p80 subunit targets theenzyme to the centrosome. Katanin is a member of the AAA family ofATPases.
Catalog Number:
(10389-526)
Supplier:
Bioss
Description:
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
Catalog Number:
(10663-378)
Supplier:
Bioss
Description:
GPKOW is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.
Catalog Number:
(103393-086)
Supplier:
Novus Biologicals
Description:
The Goat anti-Human IgA / IgG / IgM Secondary Antibody [FITC] from Novus Biologicals is a goat polyclonal antibody to IgA / IgG / IgM. This antibody reacts with human. The Goat anti-Human IgA / IgG / IgM Secondary Antibody [FITC] has been validated for the following applications: Flow Cytometry, Immunomicroscopy.
Catalog Number:
(103392-852)
Supplier:
Novus Biologicals
Description:
The Mouse anti-Human IgG4 Fc fragment Secondary Antibody (5C7) [FITC] from Novus Biologicals is a mouse monoclonal antibody to IgG4 Fc fragment. This antibody reacts with human. The Mouse anti-Human IgG4 Fc fragment Secondary Antibody (5C7) [FITC] has been validated for the following applications: ELISA.
Catalog Number:
(103391-932)
Supplier:
Novus Biologicals
Description:
The Mouse anti-Human IgG Fc fragment Secondary Antibody (3D3) [FITC] from Novus Biologicals is a mouse monoclonal antibody to IgG Fc fragment. This antibody reacts with human. The Mouse anti-Human IgG Fc fragment Secondary Antibody (3D3) [FITC] has been validated for the following applications: ELISA.
Catalog Number:
(103400-230)
Supplier:
Novus Biologicals
Description:
The CD23 / Fc epsilon RII Antibody (EBVCS2) [FITC] from Novus Biologicals is a mouse monoclonal antibody to CD23 / Fc epsilon RII. This antibody reacts with human. The CD23 / Fc epsilon RII Antibody (EBVCS2) [FITC] has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.
Supplier:
Sino Biological
Description:
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD4 (rh CD4; Catalog#10400-H08H; NP_000607.1; Met1-Trp390) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Supplier:
Sino Biological
Description:
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD31 / PECAM-1 (rh CD31 / PECAM-1; Catalog#10148-H08H; EAW94208.1; Met1-Lys601) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Supplier:
Sino Biological
Description:
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Ferret CD4 (rF CD4; Catalog#60003-F08H; ABS50090.1; Met 1-Leu 401) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Catalog Number:
(10298-872)
Supplier:
Bioss
Description:
Nuclear Marker.The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Catalog Number:
(10262-614)
Supplier:
Bioss
Description:
Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.
Catalog Number:
(10239-380)
Supplier:
Bioss
Description:
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity). The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
Catalog Number:
(10278-622)
Supplier:
Bioss
Description:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
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