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Pentafluorophenyl+isothiocyanate
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Pentafluorophenyl+isothiocyanate
Catalog Number:
(10260-270)
Supplier:
Bioss
Description:
Prion diseases or transmissible spongiform encephalopathies (TSEs) are manifested as genetic, infectious or sporadic, lethal neurodegenerative disorders involving alterations of the prion protein (PrP). Infectious PrPSc is highly expressed in the brain of animals affected by TSEs, including scrapie in sheep, BSE in cattle, and Cruetzfeldt-Jacob disease in humans. The PRND gene locus, located on human chromosome 20p, encodes for the doppel protein (Dpl), which exhibits approximately 25% sequence homology with PrP. Dpl is characterized by an alpha-helical conformation, intramolecular disulfide bonds, and two N-linked oligosaccharides, and it is presented on the cell surface by a glycosylphosphatidylinositol anchor. Dpl is highly expressed in adult testis and heart and is detectable in the brain of neonatal mice. Dpl does not appear to contribute to prion disease progression, but ectopic expression of Dpl is implicated in neuronal degeneration of ataxic PRP-deficient mice. Dpl is also thought to play a role in angiogenesis, specifically maturation of the blood-brain barrier.
Catalog Number:
(89292-760)
Supplier:
Genetex
Description:
Rat monoclonal antibody [TY25] to PD-L2
Catalog Number:
(89329-716)
Supplier:
Genetex
Description:
Clone: LT20 Conjugation: FITC Purity: Protein A purified Species Reactivity: Human Tested Applications: FACS Pkg Size: 100 test
Catalog Number:
(76834-640)
Supplier:
ANTIBODIES.COM LLC
Description:
Goat F(ab')2 anti-mouse IgG Fc (FITC) secondary antibody for IHC, ICC, Flow Cytometry and IF with samples derived from Mouse.
Catalog Number:
(89279-564)
Supplier:
Genetex
Description:
Mouse monoclonal antibody [Bu14] to CD55
Catalog Number:
(89278-310)
Supplier:
Genetex
Description:
Mouse monoclonal antibody [2H7] to CD20
Catalog Number:
(10706-716)
Supplier:
Abnova
Description:
Mouse monoclonal antibody raised against native CD59.
Catalog Number:
(10705-888)
Supplier:
Abnova
Description:
Mouse monoclonal antibody raised against native CD14.
Catalog Number:
(10718-582)
Supplier:
Abnova
Description:
Rat monoclonal antibody raised against Icam2.
Catalog Number:
(RL012-0204)
Catalog Number:
(76957-298)
Supplier:
ANTIBODIES.COM LLC
Description:
Mouse monoclonal [E11] antibody to CD35 (FITC) for Flow Cytometry with samples derived from Human and Non-Human Primates.
Catalog Number:
(89331-186)
Supplier:
Genetex
Description:
Purity: Purified by protein A chromatography or sequential differential precipitations Species Reactivity: Bacteria Tested Applications: ICC/IF, IP Pkg Size: 500 ul
Catalog Number:
(89287-076)
Supplier:
Genetex
Description:
Mouse antibody to CD16 (FITC)
Catalog Number:
(10071-558)
Supplier:
Prosci
Description:
Monoclonal antibody HIV -FITC Host: Mouse Clone no: 1943 Species reactivity: Virus isotype: IgG1 Tested application: ELISA, WB, IHC, IF
Catalog Number:
(10306-090)
Supplier:
Bioss
Description:
The nuclear envelope separates the nucleoplasm from the cytoplasm in eukaryotic cells and includes the outer and inner nuclear membrane, nuclear pore complexes and the nuclear lamina. The nuclear lamina contains intermediate filament-type proteins called lamins that form a dense network to strengthen and stabilize the nuclear envelope. Lamina-associated polypeptide 2 (LAP2) is also known as thymopoietin. LAP2 is a nuclear envelope protein and contains an amino-terminal region called the LAP2-emerin-MAN1 or LEM motif. LAP2 also contains a unique DNA-binding amino-terminal domain. Alternative splicing produces six isoforms (, _,_, and ) of mammalian LAP2 and three isoforms in Xenopus LAP2. LAP2 and LAP2_ associate with chromosomal barrier-to-autointegration factor (BAF) and may play a role in stabilizing chromatin structure. LAP2_ also binds to lamin B. LAP2 is a non-membrane isoform of LAP2 that associates with the internal nucleoskeleton and binds lamin A. The gene encoding human LAP2 maps to chromosome 12q23.1.
Catalog Number:
(10305-222)
Supplier:
Bioss
Description:
The claudin superfamily consists of many structurally related proteins that are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. It is suggested that the claudin family of proteins regulate transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specific regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-22, also known as CLDN22, is a 220 amino acid member of the claudin family that participates in tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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