Potassium+(tert-butoxymethyl)trifluoroborate
Catalog Number:
(RCR2236030-1A)
Catalog Number:
(76083-958)
Supplier:
Bioss
Description:
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Catalog Number:
(RLKHB002)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgG (H&L) Reacts with Mouse
Catalog Number:
(RL606-4003)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG F(c) Reacts with Guinea Pig
Supplier:
Spectrum Chemicals
Description:
Pyridoxine Hydrochloride, USP is a form of vitamin B6.Â
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Catalog Number:
(RL607-1902)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgG (H&L) Reacts with Hamster
Catalog Number:
(RL605-702-002)
Supplier:
Rockland Immunochemical
Description:
Secondary Donkey Anti-IgG (H&L) Reacts with Goat
Catalog Number:
(14228-798)
Supplier:
Argos Technologies
Description:
Automatic gas shutoff feature ensures operator safety.
Catalog Number:
(76118-600)
Supplier:
Bioss
Description:
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Catalog Number:
(10288-042)
Supplier:
Bioss
Description:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Catalog Number:
(RL611-6602)
Supplier:
Rockland Immunochemical
Description:
Secondary Sheep Anti-IgG (H&L) Reacts with Rabbit (Lapine)
Catalog Number:
(10271-260)
Supplier:
Bioss
Description:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.
Catalog Number:
(RL612-1006)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgA Reacts with Rat
Catalog Number:
(10101-218)
Supplier:
Prosci
Description:
The KCNIP2 gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium.
Catalog Number:
(10237-204)
Supplier:
Bioss
Description:
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Calcium is required for high affinity binding to GABA. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception. Activated by (-)-baclofen, cgp27492 and blocked by phaclofen. Isoform 1E may regulate the formation of functional GABBR1/GABBR2 heterodimers by competing for GABBR2 binding. This could explain the observation that certain small molecule ligands exhibit differential affinity for central versus peripheral sites.
Catalog Number:
(RL616-4902)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgG (H&L) Reacts with Donkey
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