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2-Methoxy-5-methylphenylboronic+acid
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2-Methoxy-5-methylphenylboronic+acid
Catalog Number:
(10269-996)
Supplier:
Bioss
Description:
Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.
Catalog Number:
(76062-214)
Supplier:
Prosci
Description:
For WB starting dilution is: 1:1000
Catalog Number:
(76169-468)
Supplier:
Thermo Scientific
Description:
Reliable liquid temperature control, with cooling capacity up to 2000 w/6830 BTU.
Catalog Number:
(RL202-4107)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgM mu chain Reacts with Cat (Feline)
Catalog Number:
(RL102-4107)
Supplier:
Rockland Immunochemical
Description:
Secondary Rabbit Anti-IgM mu chain Reacts with Cat (Feline)
Catalog Number:
(75931-858)
Supplier:
Rockland Immunochemical
Description:
Sheep IgG F(ab')2 Fragment
Catalog Number:
(RLB310)
Supplier:
Rockland Immunochemical
Description:
The whole sera are prepared from normal sera by a multi-step process that includes delipidation and selective precipitation
Catalog Number:
(10333-530)
Supplier:
Bioss
Description:
Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.
Catalog Number:
(76010-922)
Supplier:
Prosci
Description:
Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
Catalog Number:
(EM1.04724.0025)
Catalog Number:
(76069-620)
Supplier:
Prosci
Description:
For WB starting dilution is: 1:1000
Catalog Number:
(76063-060)
Supplier:
Prosci
Description:
For WB starting dilution is: 1:1000
Catalog Number:
(RL610-701-002)
Supplier:
Rockland Immunochemical
Description:
Secondary Donkey Anti-IgG (H&L) Reacts with Mouse
Supplier:
BeanTown Chemical
Description:
CAS: 5970-45-6; EC No: 209-170-2; MDL No: MFCD00066961; RTECS: ZG8750000
UN No: UN3077; Haz Class: 9; Packing Group: III
Powder; Linear Formula: Zn(CH3COO)2·2H2O; MW: 219.50
Melting Point: 237°
Density (g/mL): 1.84
Catalog Number:
(RL617-102-007)
Supplier:
Rockland Immunochemical
Description:
Secondary Goat Anti-IgM (mu chain) Reacts with Monkey
Catalog Number:
(75931-478)
Supplier:
Rockland Immunochemical
Description:
Rat IgG F(ab')2 Fragment
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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