Sodium+hypophosphite+monohydrate
Catalog Number:
(75842-534)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The GARP5 monoclonal antibody specifically reacts with human Glycoprotein A Repetitions Predominant (GARP, also known as LRRC32 or Garpin) molecule, a 80 kDa transmembrane glycoprotein expressed on the cell surface. GARP is expressed in activated Treg cells, placenta, pancreas, liver, skeletal muscle, heart, lung, and kidney, and it acts as a receptor for latent TGF-β, which down-regulates the Treg cells action. 
Catalog Number:
(RL810-1302)
Supplier:
Rockland Immunochemical
Description:
Mouse IgG (H&L) peroxidase conjugated Antibody is suitable for immunoblotting (western or dot blot), ELISA, immunoperoxidase electron microscopy and immunochemistry as well as other peroxidase-antibody based enzymatic assays requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.
Catalog Number:
(75841-696)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Catalog Number:
(75842-778)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
Catalog Number:
(75843-172)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The 3D12 monoclonal antibody specifically reacts with human CD197 (CCR7 or EBI-1), a seven-transmembrane G-protein-coupled. It is the receptor for the secondary lymphoid-tissue chemokine (SLC or 6CKine), CCL19, and CCL21. CD197 is expressed on subsets of B and T cells, and mature dendritic cells. The monoclonal 3D12 antibody recognizes the N-terminus of the receptor.
We recommend that this antibody be incubated for at least 45 minutes at 4°C for optimal staining.
Catalog Number:
(75843-216)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The RM134L monoclonal antibody specifically reacts with mouse CD252, a TNF/NGF superfamily member present on activated B lymphocytes and antigen-presenting cells. On activated B cells it enhances immunoglobulin secretion and cell proliferation. CD252 is also known as the OX-40 ligand and interacts with the OX-40 antigen found on the surface of activated T cells. The RML134L is reported to block the costimulatory activity of OX-40L.
Catalog Number:
(75844-412)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The P1H12 monoclonal antibody reacts with CD146, 118kDA transmembrane glycoprotein that is also called the melanoma cell adhesion molecule (Mel-CAM), MUC18, Endo-CAM, and S-Endo. It is a prominently glycosylated protein with carbohydrates comprising the majority of its mass and it is expressed on melanoma, stromal, endothelial, and bone marrow fibroblasts. The P1H12 antibody cross reacts with human, mouse, canine, rabbit to the exclusion of rat protein.
Catalog Number:
(75841-648)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The DREG-56 monoclonal antibody specifically reacts with human CD62L, also known as L-selectin and LECAM-1. It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). CD62L is expressed on monocytes, NK cells, neutrophils, granulocytes, and subsets of T and B cells. It is reported that the DREG-56 antibody inhibits the binding of lymphocytes to HEV tissue in frozen peripheral tissue.
Catalog Number:
(75841-766)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The Sa2-8 monoclonal antibody specifically reacts with mouse CD14, a cell surface anchored glycoprotein that is primarily expressed on macrophages and is secreted in certain conditions. CD14 associates with LPS and LBP to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The Sa2-8 antibody exhibits a weak antagonistic activate in relation to TNF alpha production and NF-kappa B activation.
Catalog Number:
(75843-602)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The D7 monoclonal antibody specifically reacts with mouse Ly-6A/E (Sca-1), a 18 kDa GPI-linked surface protein. It is expressed on multipotent hematopoietic stem cells (HSC) and subsets of B and T cells and involved in B and T cell lymphocyte responses. Splenocytes from Ly-6.2 strains exhibit a larger number of D7-positive cells than those from the Ly-6.1 strains.
Catalog Number:
(75843-118)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM). It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
Catalog Number:
(75843-032)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.
Catalog Number:
(75843-608)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The D7 monoclonal antibody specifically reacts with mouse Ly-6A/E (Sca-1), a 18 kDa GPI-linked surface protein. It is expressed on multipotent hematopoietic stem cells (HSC) and subsets of B and T cells and involved in B and T cell lymphocyte responses. Splenocytes from Ly-6.2 strains exhibit a larger number of D7-positive cells than those from the Ly-6.1 strains.
Catalog Number:
(75843-534)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The TER-119 monoclonal antibody specifically binds to the mouse 52 kDa Glycophorin A expressed on the erythroid lineage cells, from the early proerythroblast to mature erythrocyte stages, in the fetal liver, adult bone marrow, newborn liver, yolk sac, and adult lymphoid organs. The TER-119 antibody is used, together with other antibodies, as a marker for hematopoietic lineages cells.
Catalog Number:
(75842-918)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction.The OKT3 antibody is an immunosuppressive, which has proven to be an effective therapeutic agent in liver, heart, and renal allograft rejection.
Catalog Number:
(75842-174)
Supplier:
BIOGEMS INTERNATIONAL INC.
Description:
The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.
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