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Sodium+methotrexate


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Catalog Number: (76064-680)

Supplier:  Prosci
Description:   For WB starting dilution is: 1:1000

Supplier:  Bioss
Description:   The PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
Supplier:  BIOGEMS INTERNATIONAL INC.
Description:   MOPC-21 is a Mousemyeloma protein from the Ig family. It can be used as an Isotype Control for MouseIgG1 antibodies.
Supplier:  Electron Microscopy Sciences
Description:   Methenamine Silver Method for Argentaffin Cells for staining of argentaffin granules of enterochromaffin cells, Results - Argentaffin Cells: Black, Coarse connective tissue of submucosa: Variable amount of blackening.
Minority or Woman-Owned Business Enterprise
Supplier:  MP Biomedicals
Description:   Kinetin is an adenine-type cytokinin phytohormone.
MSDS SDS
Catalog Number: (76011-120)

Supplier:  Prosci
Description:   Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
Catalog Number: (RL114-4107)

Supplier:  Rockland Immunochemical
Description:   Secondary Rabbit Anti-IgM mu chain Reacts with Pig (Swine, Porcine)
Supplier:  Bioss
Description:   Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.
Supplier:  Bioss
Description:   Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
Catalog Number: (10013-962)

Supplier:  Immunoreagents
Description:   This conjugate is suitable for immunomicroscopy and flow cytometry. The optimal working dilution should be determined by the investigator. Suggested starting dilution(?): · 1:20 - 1:2,000 for most applications
Catalog Number: (IC091440049)

Supplier:  MP Biomedicals
Description:   Ham's F10 has demonstrated satisfactory growth of primary rat, rabbit and chicken tissue explants.
Supplier:  Adipogen
Description:   Stimulant slightly ionotropic drug of the xanthine chemical class, with physiological effects similar to caffeine. It is combined with pharmaceutical drugs to form stable salts.
Catalog Number: (100504-126)

Supplier:  Electron Microscopy Sciences
Description:   Kornhauser's quad stain for most elementary structures of tissues. Stain Tech., 18, 985 (1943) Mallory's tissue stain for connective tissue. Mallory, J. Exper. Med., 5,15 (1900). Used with safranin and tannic acid for showing shoot apex in plant tissue. Stain Tech., 18, 105 (1943).
Minority or Woman-Owned Business Enterprise
Supplier:  BIOGEMS INTERNATIONAL INC.
Description:   The C1.18.4 monoclonal antibody is used as an Isotype Control for MouseIgG2a antibodies. It has unknown specificity and occurred spontaneously in a C3H mouse.
Supplier:  BIOGEMS INTERNATIONAL INC.
Description:   The C1.18.4 monoclonal antibody is used as an Isotype Control for MouseIgG2a antibodies. It has unknown specificity and occurred spontaneously in a C3H mouse.
Supplier:  BIOGEMS INTERNATIONAL INC.
Description:   MOPC-21 is a Mousemyeloma protein from the Ig family. It can be used as an Isotype Control for MouseIgG1 antibodies.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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