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Sodium+molybdate(VI)
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Sodium+molybdate(VI)
Catalog Number:
(89230-072)
Catalog Number:
(75928-184)
Supplier:
Rockland Immunochemical
Description:
Glycoprotein VI (GP6) is a 58kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. It is uniquely expressed by cells of the megakaryocytic/platelet lineage, and is a member of the immunoglobulin gene superfamily, closely related to Fc receptor gamma chain (FcRgamma) and natural killer receptors. Glycoprotein VI plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcRgamma, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2. GPVI deficiency can result in bleeding disorders. Further study should reveal the extent of GPVI involvement in thrombotic disease and allow the development of alternative anti-thrombotic compounds.
Supplier:
WORLD PRECISION INSTRUMENTS LLC
Description:
Glass and synthetic quartz cuvettes are ideal for UV/VIS/NIR absorbance or fluorescence experiments. Synthetic quartz can be used in deep UV applications and is recommended for fluorescent applications, as it does not exhibit background fluorescence. Quartz cuvettes (absorbance, fluorescence and flow) are shipped individually packaged. These economic quartz are ideal for precision measurements because of their high quality materials used and their low manufacturing tolerances.
Catalog Number:
(JTV025-05)
Supplier:
Strem Chemicals Inc
Description:
CAS #: 7790-75-2. Size: 100g.
Catalog Number:
(97064-646)
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Sodium hydroxide solution 10 N, Biotech Reagent, J.T.Baker®
Supplier:
Liveo
Description:
Translucent, platinum-cured silicone tubing for laboratory applications and pharmaceutical processes.
Catalog Number:
(BDH9300-500G)
Supplier:
VWR International
Description:
Meets reagent specifications for testing USP/NF monographs.
Catalog Number:
(10103-248)
Supplier:
Prosci
Description:
Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Collagen receptor involved in collagen-induced platelet adhesion and activation. GP6 plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2.Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets. Collagen fibers are the most thrombogenic macromolecular components of the extracellular matrix, with collagen types I, III, and VI being the major forms found in blood vessels. Platelet interaction with collagen occurs as a 2-step procedure: (1) the initial adhesion to collagen is followed by (2) an activation step leading to platelet secretion, recruitment of additional platelets, and aggregation. In physiologic conditions, the resulting platelet plug is the initial hemostatic event limiting blood loss. However, exposure of collagen after rupture of atherosclerotic plaques is a major stimulus of thrombus formation associated with myocardial infarction or stroke (Jandrot-Perrus et al., 2000 [PubMed 10961879]).[supplied by OMIM].
Catalog Number:
(89399-838)
Supplier:
HITACHI HIGH-TECH AMERICA, INC.
Description:
The ChromasterUltra Rs is the result of many years of research, development and experience, leading to the introduction of one of the most advanced, robust and easy to use UHPLC system available on the market today. Hitachi-High Technologies is a world leader in fluid control and optical analysis technology, as well as in high performance electronics. Hitachi has focused on combining the knowledge of these three key disciplines to give the world of chromatography one of the best instruments for today's demands. To arrange a demonstration with one of our experts, please email chromatography@us.vwr.com.
Catalog Number:
(JT5565-28)
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Macron Fine Chemicalsâ„¢ OR: organic reagents that are suitable for research applications.
Catalog Number:
(AA14487-09)
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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