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Succinic+acid,+[1,4-14C]
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Succinic+acid,+[1,4-14C]
Catalog Number:
(10285-548)
Supplier:
Bioss
Description:
Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.
Catalog Number:
(10285-552)
Supplier:
Bioss
Description:
Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored; for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.
Catalog Number:
(76008-978)
Supplier:
Prosci
Description:
The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied by OMIM].
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Sumatriptan succinate
Catalog Number:
(77549-596)
Supplier:
AMBEED, INC
Description:
Potassium succinate ≥98%
Catalog Number:
(TS46269-0010)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Loxapine succinate
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
Chloramphenicol sodium succinate 98-102%
Catalog Number:
(TCT3118-5G)
Supplier:
TCI America
Description:
alpha-Tocopherol polyethylene glycol succinate
Supplier:
Matrix Scientific
Description:
1-Ethyl-4-(2-oxo-1,2-diphenylethyl)succinate 97
Supplier:
AMBEED, INC
Description:
Trelagliptin succinate 98+%
Catalog Number:
(95033-028)
Supplier:
Spectrum Chemicals
Description:
Doxylamine Succinate, USP is an antihistamine, used to relieve symptoms of allergy, hay fever, and the common cold. All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Supplier:
AMBEED, INC
Description:
Di-tert-butyl succinate ≥95%
Catalog Number:
(77300-586)
Supplier:
AMBEED, INC
Description:
Potassium succinate trihydrate 98%
Supplier:
TCI America
Description:
Solifenacin Succinate, Purity: >98.0%(HPLC), Cas number: 242478-38-2, Molecular Formula: C23H26N2O2.C4H6O4, Molecular Weight: 480.56, Appearance: White - Almost white solid crystal powder, Size: 100MG
Catalog Number:
(76841-490)
Supplier:
AMBEED, INC
Description:
2-Ethyl-3-hydroxy-6-methylpyridine succinate 97%
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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