(1H-Benzoimidazol-2-yl)methanol
Catalog Number:
(EM8.24456.0500)
Supplier:
MilliporeSigma
Description:
(2S, 4R)-(-)-Ethyl 4-hydroxy-2-pyrrolidincarboxylate hydrochloride, CAS no : 33996-30-4, Synonyms L-4-Hydroxyproline ethyl ester hydrochloride, for synthesis, 500mg
Supplier:
AMBEED, INC
Description:
3,4,5-Trichlorothiophene-2-carboxylic acid, Purity: 95%, CAS Number: 26020-48-4, Appearance: Solid or liquid, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 5g
Catalog Number:
(77254-716)
Supplier:
AMBEED, INC
Description:
2,3,4,5-Tetrachloronitrobenzene, Purity: 97%, CAS Number: 879-39-0, Appearance: White to pale-yellow powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 1g
Catalog Number:
(I-1595.0050BA)
Supplier:
Bachem Americas
Description:
Sequence: Boc-Gln-Gly-Arg-AMC · HCl
Supplier:
TCI America
Description:
CAS Number: 33286-22-5
MDL Number: MFCD00069252 Molecular Formula: C22H26N2O4S Molecular Weight: 450.98 Purity/Analysis Method: >98.0% (HPLC,T) Form: Crystal Melting point (°C): 210 Specific rotation [a]20/D: 118 deg (C=1, H2O) Storage Temperature: 0-10°C
Supplier:
MP Biomedicals
Description:
Ready-to-use proteinase K solution, 20 mg/ml in 10 mM Tris-HCl, 1 mM calcium acetate, pH 7.5 containing 50% glycerol.
Catalog Number:
(95043-782)
Supplier:
Enzo Life Sciences
Description:
Glucose-regulated protein 94 (Grp94, gp96), an abundant resident endoplasmic reticulum (ER) lumenal stress protein, belongs to the Hsp90 family of molecular chaperones along with cytosolic Hsp90. Grp94 and such other resident soluble proteins of the ER as the Ca 2+ binding protein subfamily (CaBP, CaBPI, CaBP2 and calreticulin) possess the C-terminal tetrapeptide Lys-Asp-Glu-Leu (KDEL), a sorting signal considered responsible for the retention of these proteins in the pre-Golgi compartments. Stress conditions such as glucose starvation and heat shock which promote protein misfolding or unfolding increase Grp94 expression. In addition to a homeostatic role in protein folding and assembly, Grp94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. Grp94 and Hsp90 share high sequence identity and apparently identical adenosine nucleotide dependent modes of regulation, although previous data suggests that Hsp90 and Grp94 may differ in their nucleotide binding properties. The N-terminal domain of eukaryotic Hsp90 proteins contains a conserved adenosine nucleotide binding pocket which also serves as the binding site for the Hsp90 inhibitors geldanamycin and radicicol. However, the molecular basis for adenosine nucleotide-dependent regulation of Grp94 remains unclear. Data supports a ligand dependent regulation of Grp94 function, and suggests a model whereby Grp94 function is regulated through a ligand -dependent conversion of Grp94 from an inactive to an active conformation.
Supplier:
Matrix Scientific
Description:
MF=C5HCL2N3 MW=173.99 CAS=3177-24-0 MDL=MFCD09746248 1G
Catalog Number:
(TS16059-0050)
Supplier:
THERMO FISHER SCIENTIFIC CHEMICALS
Description:
3,4,5-Trichloropyridazine 98%
Supplier:
Bachem Americas
Description:
Sequence: H-Ala-pNA · HCl
Catalog Number:
(80017-408)
Supplier:
MilliporeSigma
Description:
BAY 61-3606, 2-(7-(3,4-Dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino)-nicotinamide, HCl
Supplier:
AMBEED, INC
Description:
D-Allo-isoleucine ethyl ester hydrochloride 97+%
Supplier:
AMBEED, INC
Description:
GSK-484 hydrochloride ≥98%
Supplier:
AMBEED, INC
Description:
N1-(4-Chlorobenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine hydrochloride, Purity: 98%, CAS Number: 6170-42-9, Appearance: Solid, Storage: Inert atmosphere, Room Temperature, Size: 1MG
Supplier:
Thermo Scientific Chemicals
Description:
L-Glutamic acid dibenzyl ester hydrochloride, Purity: 98%, Cas number: 4561-10-8, Molecular formula: C19H21NO4.HCl, Color: Whiter, Form: Powder, Synonyms: H-Glu(OBzl)-Obzl.HCl, 1G
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