2,2-Bis(4-cyanatophenyl)propane
Supplier:
AMBEED, INC
Description:
N-(tert-Butoxycarbonyl)-7-aminoheptanoic acid 97%
Supplier:
VWR International
Description:
Ensure the security of sanitary connections with preset torque output.
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Catalog Number:
(103404-596)
Supplier:
Novus Biologicals
Description:
The Bcl-xL Antibody (BX006) - Azide and BSA Free from Novus Biologicals is a mouse monoclonal antibody to Bcl-xL. This antibody reacts with human, mouse, rat, porcine. The Bcl-xL Antibody (BX006) - Azide and BSA Free has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry / Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.
Supplier:
AMBEED, INC
Description:
(R)-3-((tert-Butoxycarbonyl)amino)-3-(4-chlorophenyl)propanoic acid, Purity: 98%, CAS number: 479064-93-2, Appearance: White to Yellow Solid, Storage: Sealed in dry, Room Temperature, Size: 250MG
Catalog Number:
(10319-904)
Supplier:
Bioss
Description:
Ubiquitin: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in lysosomal degradation; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
Supplier:
AMBEED, INC
Description:
(R)-3-(4-Bromophenyl)-3-((tert-butoxycarbonyl)amino)propanoic acid, Purity: 97%, CAS number: 261380-20-5, Appearance: White to Yellow Solid, Storage: Sealed in dry, 2-8C, Size: 1G
Catalog Number:
(76480-624)
Supplier:
AAT BIOQUEST INC
Description:
A variety of cyanine 3 (Cy3®) dyes has been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis.
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Supplier:
AMBEED, INC
Description:
(S)-2-((tert-Butoxycarbonyl)amino)-3-(2,4-dichlorophenyl)propanoic acid, Purity: 97%, CAS number: 114873-04-0, Appearance: Form: powder Colour: white - beige, Storage: Sealed in dry, 2-8C, Size: 1G
Catalog Number:
(10424-786)
Supplier:
Bioss
Description:
ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries, in search of brain-specific proteins. Two splice variants with different carboxyterminal ends were described. The message was found only in the brain in this publication. Another group identified ADAM11 in the human brain, where ADAM11 was thought to be involved in cell migration and spatial patterning. ADAM11 was mapped to 17q21.3, a region of interest for breast cancer, and mutations in ADAM11 are associated with some breast cancers. Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, a human embryonic carcinoma cell line. ADAM11 null mutant mice have deficits in spatial learning and motor coordination, although they did have normal cell migration and differentiation during development. ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full-length ADAM11 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a spacer region, then the transmembrane domain and a short cytoplasmic domain.
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 041359-5G , MDL Number: MFCD00063356
Catalog Number:
(76193-996)
Supplier:
Prosci
Description:
This mAb recognizes a protein of 134kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This mAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This mAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.
Supplier:
AMBEED, INC
Description:
(R)-3-((tert-Butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoic acid, Purity: 98+%, CAS number: 479064-94-3, Appearance: White to off-white powder or crystals, Storage: Sealed in dry, 2-8C, Size: 1G
Catalog Number:
(10424-958)
Supplier:
Bioss
Description:
ADAM11 was first described as MDC (Metalloproteinase-like disintergin-like cysteine-rich protein) from analysis of human brain libraries, in search of brain-specific proteins. Two splice variants with different carboxyterminal ends were described. The message was found only in the brain in this publication. Another group identified ADAM11 in the human brain, where ADAM11 was thought to be involved in cell migration and spatial patterning. ADAM11 was mapped to 17q21.3, a region of interest for breast cancer, and mutations in ADAM11 are associated with some breast cancers. Retinoic acid caused a doubling in ADAM11 message levels over 24 hours in NT2/D1 cells, a human embryonic carcinoma cell line. ADAM11 null mutant mice have deficits in spatial learning and motor coordination, although they did have normal cell migration and differentiation during development. ADAM11 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full-length ADAM11 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a spacer region, then the transmembrane domain and a short cytoplasmic domain.
Supplier:
AMBEED, INC
Description:
(R)-2-((tert-Butoxycarbonyl)amino)-3-(2,4-dichlorophenyl)propanoic acid, Purity: 97%, CAS number: 114873-12-0, Appearance: Form: powder Colour: white - beige, Storage: Sealed in dry, Room Temperature, Size: 250MG
Supplier:
Adipogen
Description:
A sensitive reagent for measuring the free sulfhydryl content in proteins, peptides, and tissues. Used to characterize reactive thiol groups and photometric determination of thiols and for measuring low-molecular mass thiols such as glutathione in both pure solutions and biological samples, such as blood. It can also measure the number of thiol groups on proteins. Through reaction with aliphatic thiol groups a mixed disulfide of protein thiol and one mole of 2-nitro-5-thiobenzoate per mole of protein sulfhydryl group is being formed. DTNB has little absorbance. Reaction with -SH groups on proteins (from any solvent accessible Cys) under mild alkaline conditions (pH 7-8) produces the 2-nitro-5-thiobenzoate anion, which gives an intense yellow color with an absorption maximum at 409.5nm (Extinction coefficient: 14150 M-1*cm-1). Sensitive to various buffer ions, therefore, the extinction coefficient used to calculate the number of sulfhydryl groups must be matched to the reaction conditions. In case the thiol groups are in disulfide bonds, they must be reduced under anaerobic conditions prior to reaction with DTNB.
Catalog Number:
(103408-760)
Supplier:
Novus Biologicals
Description:
The LIMS2 Antibody from Novus Biologicals is a goat polyclonal antibody to LIMS2. This antibody reacts with human. The LIMS2 Antibody has been validated for the following applications: Peptide ELISA.
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