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Trimethyl(vinyloxy)silane
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Trimethyl(vinyloxy)silane
Supplier:
Adipogen
Description:
Chirality inducing agent. Useful tool as resolving agent to separate the isomers and purify racemic mixtures (e.g. DL-lysine) by fractionally crystallizing the product to obtain the pure isomer (e.g. D-lysine). Can also be used as building block.
Supplier:
TCI America
Description:
CAS Number: 1760-24-3
MDL Number: MFCD00008173 Molecular Formula: C8H22N2O3Si Molecular Weight: 222.36 Purity/Analysis Method: >97.0% (GC) Form: Clear Liquid Boiling point (°C): 146 Flash Point (°C): 143 Specific Gravity (20/20): 1.03
Catalog Number:
(10265-920)
Supplier:
Bioss
Description:
BPTF is a 2,907 amino acid protein encoded by the human gene BPTF. BPTF belongs to the PBTF family and contains one bromodomain, one DDT domain and two PHD-type zinc fingers. BPTF acts as a histone-binding component of NURF (nucleosome-remodeling factor). The NURF complex, which consists of SMARCA1, BPTF, RbAp46 and RbAp48, acts to catalyze ATP-dependent nucleosome sliding and facilitates transcription of chromatin. It specifically recognizes histone H3 tails trimethylated on 'Lys-4' (H3-K4Me3), which mark transcription start sites of virtually all active genes. BPTF may also help regulate transcription through direct binding to DNA or transcription factors.
Catalog Number:
(76100-770)
Supplier:
Bioss
Description:
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone demethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 (By similarity).
Catalog Number:
(76100-772)
Supplier:
Bioss
Description:
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone demethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 (By similarity).
Catalog Number:
(10068-700)
Supplier:
Prosci
Description:
Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Inhibits the intrinsic kinase activity of TAF1. In case of viral infections, interactions with SV40 large T antigen, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity.
Supplier:
BeanTown Chemical
Description:
CAS: 95-63-6; EC No: 202-436-9; MDL No: MFCD00008527; RTECS: DC3325000
UN No: UN3295; Haz Class: 3; Packing Group: III
Liquid; Molecular Formula: C9H12; MW: 120.19
Melting Point: -44°; Boiling Point: 168°; Flash point: 48°C (118°F)
Density (g/mL): 0.876; Refractive Index: 1.504
Supplier:
MP Biomedicals
Description:
Amphotericin B is used as antifungal in cell culture media. Amphotericin B is a polyene antifungal, antibiotic from <i>Streptomyces sp</i>. It has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. It is an antibiotic solution effective against yeast and other fungi. Amphotericin B may be toxic to some insect cell types. Amphotericin B, is an antimycotic.
Supplier:
TCI America
Description:
CAS Number: 108-75-8
MDL Number: MFCD00006338 Molecular Formula: C8H11N Molecular Weight: 121.18 Purity/Analysis Method: >98.0% (GC,T) Form: Clear Liquid Color: Colorless Boiling point (°C): 171 Melting point (°C): -43 Flash Point (°C): 58 Specific Gravity (20/20): 0.92
Supplier:
BeanTown Chemical
Description:
CAS: 700-13-0; EC No: 211-838-3; MDL No: MFCD00002346; RTECS: MX7820000
UN No: UN3077; Haz Class: 9; Packing Group: III
Powder; Linear Formula: C6H(CH3)3(OH)2; Molecular Formula: C9H12O2; MW: 152.20
Melting Point: 169-172°; Flash point: 140°C (284°F)
Supplier:
BeanTown Chemical
Description:
CAS: 98-55-5; EC No: 202-680-6; MDL No: MFCD00001557; RTECS: WZ6700000
Liquid ; Molecular Formula: C10H18O; MW: 154.24
Melting Point: 31-35°; Boiling Point: 217-218°; Flash point: 90°C (194°F)
Density (g/mL): 0.93; Refractive Index: 1.482
Supplier:
TCI America
Description:
CAS Number: 1640-39-7
MDL Number: MFCD00005724 Molecular Formula: C11H13N Molecular Weight: 159.23 Purity/Analysis Method: >97.0% (N) Form: Clear Liquid Color: Pale Yellow Boiling point (°C): 229 Flash Point (°C): 93 Specific Gravity (20/20): 0.99
Catalog Number:
(RL600-401-J98)
Supplier:
Rockland Immunochemical
Description:
Anti-Histone H3 K4-Me3/K9-Ac antibody is useful for dot blot and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~15.4kDa corresponding to the appropriate cell lysate or extract.
Supplier:
Adipogen
Description:
Chirality inducing agent. Useful tool as resolving agent to separate the isomers and purify racemic mixtures (e.g. DL-lysine) by fractionally crystallizing the product to obtain the pure isomer (e.g. D-lysine). Can also be used as building block.
Catalog Number:
(10449-118)
Supplier:
Bioss
Description:
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Sequence similarities Belongs to the histone-lysine methyltransferase family. EZ subfamily.Contains 1 SET domain.
Catalog Number:
(10275-142)
Supplier:
Bioss
Description:
JMJD2B is a 1,064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure; the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereby playing a role in histone code. It does not demethylate Histone H3 Lys 4, H3 Lys 27, H3 Lys 36 or H4 Lys 20, however, and is only able to demethylate trimethylated H3 Lys-9 and has weaker activity than JMJD2A, JMJD2C and JMJD2D. JMJD2B demethyl-ation of Lysine residues will generate formaldehyde and succinate. JMJD2B is a ubiquitously expressed nuclear protein.
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