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cis-3-Aminocyclopentanecarboxylic+acid+hydrochloride
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cis-3-Aminocyclopentanecarboxylic+acid+hydrochloride
Catalog Number:
(10287-536)
Supplier:
Bioss
Description:
The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed “orphan receptors†because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.
Catalog Number:
(10287-528)
Supplier:
Bioss
Description:
The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed “orphan receptors†because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.
Supplier:
Ricca Chemical
Description:
C.I. 13025; p-[[p-(dimethylamino)phenyl]azo]benzenesulfonic acid, sodium salt. CAS RN 547-58-0. Formula Weight: 327.33. Solution, 0.1% (w/v). pH 3.2 (pink)-4.4 (yellow). Packaged in a plastic container. 1L.
Supplier:
Spectrum Chemicals
Description:
FD and C Red No. 3 | Non-graded FD and C Red No. 3 supplied by Spectrum is indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
Catalog Number:
(EM-MX0100-20)
Catalog Number:
(100504-078)
Supplier:
Electron Microscopy Sciences
Description:
Grocott's method for fungi. Dahl's method as a bone and calcium stain. McManus' method for glycogen. Fraser-Lendrum method as a connective tissue stain.
Catalog Number:
(101410-902)
Supplier:
Electron Microscopy Sciences
Description:
1% Aqueous
Catalog Number:
(EM1.01306.0025)
Catalog Number:
(TCE0798-25G)
Supplier:
TCI America
Description:
CAS Number: 121-39-1
MDL Number: MFCD00005123 Molecular Formula: C11H12O3 Molecular Weight: 192.21 Purity/Analysis Method: >90.0% (GC) Form: Clear Liquid Boiling point (°C): 152 Flash Point (°C): 113 Specific Gravity (20/20): 1.13 Specific rotation [a]20/D: 0 deg (neat) Storage Temperature: 0-10°C
Catalog Number:
(77440-044)
Supplier:
Bioss
Description:
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (<i>in vitro</i>).
Supplier:
Spectrum Chemicals
Description:
FD and C Blue No. 2 - In the United States, the Food and Drug Administration (FDA) controls the specifications for Food, Drug and Cosmetic (FD&C) colors.
Catalog Number:
(10287-530)
Supplier:
Bioss
Description:
The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and binds DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, and several novel receptors including LXR (also referred to as RLD-1) and FXR. FXR and LXR fall into a category of proteins termed “orphan receptors†because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid.
Supplier:
Matrix Scientific
Description:
MF=C11H19NO5 MW=245.28 CAS=102195-79-9 MDL=MFCD00237541 1G
Catalog Number:
(76082-166)
Supplier:
Bioss
Description:
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Catalog Number:
(76098-900)
Supplier:
Bioss
Description:
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid (By similarity). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Supplier:
AMBEED, INC
Description:
(2S,3R)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid, Purity: 98%, CAS Number: 186132-96-7, Appearance: White to yellow powder or crystals, Storage: Sealed in dry, 2-8C, Size: 100MG
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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