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5-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
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5-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
Supplier:
G-Biosciences
Description:
Ponceau S is a rapid and reversible stain for detecting protein bands on Western blot membranes and can be used with PVDF, nitrocellulose and cellulose acetate membranes*. Ponceau S is a negative stain, which binds to the positively charged amino groups of the protein and it also binds non‐covalently to non‐polar regions in the protein.
Catalog Number:
(76082-702)
Supplier:
Bioss
Description:
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.
Catalog Number:
(76737-416)
Supplier:
ANTIBODIES.COM LLC
Description:
Human Cyclophilin F ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i><i>in vitro</i></i> quantitative determination of human Cyclophilin F in serum, plasma, tissue homogenates, and other biological fluids.
Catalog Number:
(103331-560)
Supplier:
Novus Biologicals
Description:
The NDUFV1 Antibody (4A7) from Novus Biologicals is a mouse monoclonal antibody to NDUFV1. This antibody reacts with human, rat. The NDUFV1 Antibody (4A7) has been validated for the following applications: Western Blot, ELISA, RNA Inhibition.
Supplier:
AVANTOR PERFORMANCE MATERIALS US
Description:
Polysorbate 80 utilizes ingredients of non-animal origin and non-peanut origin.
Catalog Number:
(10291-058)
Supplier:
Bioss
Description:
FKBP25 is a member of the immunophilin protein family. The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. They inhibit T-cell proliferation by interrupting two specific cytoplasmic signal transmission pathways. FKBP25 is localized in the nucleus and is expressed in the brain, testis, ovary, and spleen. It may influence immunoregulation and cerebellum development, as well as protein folding and trafficking in neurons. FKBP25 associates with transcriptional repressor protein YY1 and histone deaceltylases, HDAC1 and HDAC2. FKBP25 may contain several casein kinase II phosphorylation sites, which are believed to be important for cell growth regulation.
Catalog Number:
(10296-580)
Supplier:
Bioss
Description:
GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The protein p115 also binds p400, alternatively called giantin. Giantin, the majority of whose mass projects into the cytoplasm, is involved in the docking of COPI vesicles via p115 to the Golgi membrane. Giantin, which also is known as macrogolgin or Golgi complex-associated protein, is involved in cross-bridge formation in the Golgi complex. Giantin, which can form a homodimer, is a single-pass type I membrane protein that is an antigen in Sjoegren syndrome and in chronic rheumatoid arthritis.
Catalog Number:
(102654-110)
Supplier:
American Radiolabeled Chemicals
Description:
Synonyms: Valium [N-methyl-3H]; Ro 5-2807 [N-methyl-3H]
Catalog Number:
(10015-070)
Supplier:
Leica Biosystems
Description:
The Gill formula hematoxylins are used in the progressive method of staining.
Catalog Number:
(TCT0050-025G)
Supplier:
TCI America
Description:
CAS Number: 18472-87-2
MDL Number: MFCD00070627 Molecular Formula: C20H4Br4Cl4O5 Molecular Weight: 829.63 Purity/Analysis Method: >85.0% (E) Form: Crystal Color: Deep Yellow Red Lambda max.: 538 nm (0.02mol/L AcONH4 sol.)
Supplier:
BeanTown Chemical
Description:
CAS: 72-57-1; EC No: 200-786-7; MDL No: MFCD00003969; RTECS: QJ6475000
Solid; Molecular Formula: C34H24N6O14S4Na4; MW: 960.82
Melting Point: <gt/>300°
Catalog Number:
(89358-396)
Supplier:
Genetex
Description:
Laminin, the most abundant structural and biologically active component in basement membranes, is a complex extracellular glycoprotein with an approximate molecular weight of 900 kD. It plays an important role in many aspects of the cell biology. Laminin is composed of one A chain (400 kD) one B1 chain (215 kD) and one B2 chain (205 kD) all held together by disulfide bonds. The molecule has a cross-like form with globular units near the ends of each chain, the sites where it is bound to Collagen IV, heparan sulfate, proteoglycan as well as to the surface of epithelial cells. Laminins from various species have common antigenic determinants. Laminin is only found in significant quantities in basement membranes, the thin extracellular matrices that surround epithelial tissue, nerve, fat cells and smooth, striated and cardiac muscle. It has been found to modulate cell differentiation, cell shaping and also cell movement because it appears to be an important cell substrate-adhesion protein. Variations in the expression of this protein have been observed in embryogenesis, organogenesis, post traumatic healing and cancer. The greatest interest in laminin has been provoked by the discovery of its ability to promote neurite regeneration.
Supplier:
Biotium
Description:
This antibody recognizes a protein of 40 kDa, identified as CD7 (Workshop IV; Code T155). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Catalog Number:
(75835-444)
Supplier:
Restek
Description:
The european pharmacopoeia/ICH Class 2 mix A consists of 13 components they are, chlorobenzene (360 μg/ml), cyclohexane (3,880 μg/ml), cis-1,2-dichloroethene (1,870 μg/ml), dichloromethane (600 μg/ml), n,n-dimethylformamide (880 μg/ml), ethylbenzene (369 μg/ml), n-hexane (290 μg/ml), methylcyclohexane (1180 μg/ml), toluene (890 μg/ml), 1,1,2-trichloroethene (80 μg/ml), m-xylene (1,302 μg/ml), o-xylene (195 μg/ml) and p-xylene (304 μg/ml).
Catalog Number:
(100246-064)
Supplier:
Southern Biotechnology
Description:
CD4 is a 55 kDa type I transmembrane glycoprotein and a member of the Ig-SF of cell surface receptors. It is expressed predominantly on the “helper/inducer” subpopulation of mature T lymphocytes and on monocytes and macrophages. Domains 1 and 2 bind to MHC Class II antigens, while domains 3 and 4 may be involved in cis interactions with the CD3/TCR complex. CD4 functions as an accessory molecule in the recognition of foreign antigens in association with MHC class II antigens by T cells.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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