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SAFE AND SURE NEDERLAND B.V.
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SAFE AND SURE NEDERLAND B.V.
Catalog Number:
(76285-008)
Supplier:
Enzo Life Sciences
Description:
Recombinant monclonal antibody (Mouse IgG1κ).
Recommended Applications: ELISA, Flow Cytometry, IF, IHC, FUNC
Catalog Number:
(89161-300)
Supplier:
Enzo Life Sciences
Description:
Proteasome substrate
Catalog Number:
(89166-002)
Supplier:
Enzo Life Sciences
Description:
Membrane dye
Supplier:
Enzo Life Sciences
Description:
Cofactor of nitric oxide synthases (NOS).
Catalog Number:
(89144-390)
Supplier:
Enzo Life Sciences
Description:
Produced in E. coli. Human recombinant saposin C (aa 311-390)Â is fused at the C-terminus to a His-tag and at the N-terminus to a T-7-tag.
Catalog Number:
(89151-916)
Supplier:
Enzo Life Sciences
Description:
Highly active. Produced in CHO cells. The extracellular domain of mouse CD40L (CD154) (aa 115-260) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag.
Supplier:
Enzo Life Sciences
Description:
Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterized by the presence of at least one Bcl-2 homology (BH) domains. Bax normally resides in the cytoplasm, but following an apoptotic stimuli, Bax undergoes a conformational change and translocates to mitochondrial membranes where it inserts and mediates the release of cytochrome c. This activates caspase-3 and perpetuates the apoptotic cascade.
Catalog Number:
(76002-204)
Supplier:
Enzo Life Sciences
Description:
PP2A inhibitor
Catalog Number:
(76002-460)
Supplier:
Enzo Life Sciences
Description:
Recommended Applications: Flow Cytometry, ICC, WB
Species reactivity: Human, Mouse
Catalog Number:
(89165-752)
Supplier:
Enzo Life Sciences
Description:
Cyanine 5-dUTP can replace TTP in reactions in which it serves as a substrate for E. coli DNA polymerase (holoenzyme and Klenow fragment), T4 and Taq DNA polymerases, reverse transcriptase (from AMV and M-MuLV) and terminal transferase. Fluorescently labeled probes can be prepared with this fluorescent nucleotide by a variety of methods including nick translation, cDNA labeling and 3’-end labeling. Probes generated by these methods are suitable for use for the identification of specific sequences by in situ hybridization procedures on fixed cells and tissues by direct fluorescence detection. Cyanine 5-dUTP can also be used for multicolor fluorescence labeling.
Supplier:
Enzo Life Sciences
Description:
Synuclein was originally identified in Torpedo californica as a small neuroprotein that localized to the nuclear envelope of neurons and to presynaptic nerve termini. The human homolog was initially termed NACP, a precursor protein to NAC (Non-Ab Component), because of its prevalence in amyloid plaques in Alzheimer’s patients. Later, NACP was recognized as being alpha-Synuclein (alpha-SYN), a 14kDa protein, belonging to the synuclein family of phosphoproteins that also includes: betalpha-SYNuclein, gammalpha-SYNuclein, and synoretin.
alpha-SYN is recognized as a key component in the development and diagnosis of neurodegenerative synucleinopathic diseases (NSDs), such as Alzheimer’s and Parkinson’s disease. In the past five years, several genetic and post-translational modifications to alpha-SYN have been elucidated that have been linked to its collaboration in the formation of the classical Lewy bodies (LBs) or Lewy neurites that are associated with neurodegeneration. A study that shed more light on the neurogenesis of autorecessive synucleinopathies (ARSs) was the finding that alpha-SYN accumulation can occur due to mutations in the E3 ubiquitin ligase. ARSs only account for a small percentage of NSD. Thus the illustration that alpha-SYN has a high susceptibility to tyrosine nitration may be the key component in understanding the formation of LBs. Due to the chemical structure of alpha-SYN, tyrosine nitration readily leads to the formation of oligomers via covalent O,O’-dityrosine bonds (cross-linking). Nitrosylated, wild-type, alpha-SYN products thus form SDS-insoluble, heat-stable aggregates in vitro that may account for alpha-SYN inclusions in all forms of NSDs.
Catalog Number:
(89161-070)
Supplier:
Enzo Life Sciences
Description:
PKA inhibitor
Catalog Number:
(76284-842)
Supplier:
Enzo Life Sciences
Description:
Recombinant monclonal antibody (Rat IgG2cκ).
Recommended Applications: Flow Cytometry, WB
Catalog Number:
(10049-898)
Supplier:
Enzo Life Sciences
Description:
LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis. LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61kDa receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.
Supplier:
Enzo Life Sciences
Description:
Broad-spectrum kinase inhibitor
Catalog Number:
(89160-364)
Supplier:
Enzo Life Sciences
Description:
Nicotinamide, the water-soluble amide of nicotinic acid, is a component of the two most important coenzymes-nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate. Nicotinamide is involved in numerous oxidation-reduction reactions in mammalian biological systems acting as an antioxidant.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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