Carl Roth GmbH
Catalog Number:
(89494-406)
Supplier:
Genscript
Description:
HSA Antibody (2C7B4), mAb, Mouse recognizes HSA proteins and it has no cross-reactivity with mouse serum albumin, rabbit serum albumin, BSA and OVA.
Supplier:
Genscript
Description:
The product is specific for SARS-CoV-2 Spike Protein S1 subunit and its RBD domain.
Catalog Number:
(77007-550)
Supplier:
Genscript
Description:
Adeno-associated virus type 2 (AAV2) is a valuable vector for gene therapy. It is one member of the human parvovirus family which depends on co-infection with helper viruses such as adenovirus or herpes virus for efficient reproduction. AAV2 empty capsids are composed of three proteins, VP1, VP2 and VP3 with relative molecular masses of 87, 72 and 62 kDa respectively.
Catalog Number:
(89494-092)
Supplier:
Genscript
Description:
Recombinant Enterokinase protein
Catalog Number:
(76509-980)
Supplier:
Genscript
Description:
The product is specific for bevacizumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01975-40, anti-bevacizumab antibody (4H1), mAb, mouse.
Catalog Number:
(89495-068)
Supplier:
Genscript
Description:
The specificity of the antibody is defined as the ratio of antigen concentration to cross-reactant concentration at 50% inhibition of maximum binding.
Catalog Number:
(77007-618)
Supplier:
Genscript
Description:
CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. It plays an important role in cell proliferation and cytokine production and promotion of T-cell survival. It also enhances the production of IL-4 and IL-10 in T cells in conjunction with TCR/CD3 ligation and CD40L co-stimulation.
Catalog Number:
(76509-938)
Supplier:
Genscript
Description:
The product is specific for Adalimumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01954-40, Anti- Adalimumab Antibody (15C7), mAb, Mouse.
Catalog Number:
(77007-642)
Supplier:
Genscript
Description:
Ustekinumab with trade name Stelara, is an FDA-approved drug to Crohn's disease, Ulcerative Colitis, Plaque Psoriasis and Psoriatic Arthritis, targeting both interleukins (IL)-12 and IL-23. Ustekinumab is a fully human immunoglobulin G1 kappa mAb that binds to IL-12 and IL-23. Ustekinumab binds to the p40 subunit common to IL-12 and IL-23 and prevents their interaction with the IL-12 receptor β1 subunit of the IL-12 and IL-23 receptor complexes, thereby disrupting the proinflammatory pathway. Anti-Ustekinumab Antibody (11E3), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Ustekinumab.
Catalog Number:
(76198-392)
Supplier:
Genscript
Description:
The product is specific for Nivolumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01848-40, Anti- Nivolumab Antibody (6G5H2E6), mAb, Mouse.
Catalog Number:
(77007-584)
Supplier:
Genscript
Description:
A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.
Catalog Number:
(77007-578)
Supplier:
Genscript
Description:
Payloads are the important components of antibody-drug conjugates (ADCs). The most commonly used ADC payloads are MMAE, DM1, and DXd. ADC pharmacokinetic (PK) studies include free payload analysis, conjugated antibody analysis, and total antibody analysis via ligand-binding assay (LBA) and LC-MS/MS assay. The anti-payload antibody is a useful reagent in PK assay for determining conjugated antibodies. It can be used as a capture antibody to determine the conjugated antibody in LBA assay or through immunocapture to enrich the ADC sample in LC-MS/MS assay. The DM1, also known as mertansine, is a microtubule polymerization inhibitor. Trastuzumab emtansine (T-DM1), composed of trastuzumab conjugated to DM1, is a type of targeted cancer drug for breast cancer treatment. T-DM1 is targeted toward HER2 (ERBB2) positive breast cancer.
Catalog Number:
(89495-076)
Supplier:
Genscript
Description:
GenScript THEâ„¢ DYKDDDDK Tag antibody [FITC], mAb, Mouse recognizes C-terminal, N-terminal and internal DYKDDDDK tagged fusion proteins.
Catalog Number:
(76197-310)
Supplier:
Genscript
Description:
GenScript MonoRabâ„¢ anti-His tag (C-term) antibody (25B6E11), mAb, rabbit specifically recognizes His tags placed at C-terminal and internal regions of His-fusion
proteins. This product is not recommended for N-terminal His-fusion protein detection and nbsp.
Catalog Number:
(76510-080)
Supplier:
Genscript
Description:
The product is specific for trastuzumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A02033-40, anti-trastuzumab antibody (15H2), mAb, mouse.
Supplier:
Genscript
Description:
SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease in 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells. Lineage B.1.351 (a.k.a. 20H/501Y.V2) is a variant of SARS-CoV-2 (Beta variant). It has multiple mutations in theS1 RBD, including K417N, E484K, N501Y.
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This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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