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BIOTIUM, INC
Supplier:
Biotium
Description:
Cytokeratin 18 Monoclonal antibody, Clone: DC10, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF568, Immunogen: PMC-42 human breast carcinoma cells, Synonyms: K18, Application: IF, IHC, WB, FC, Size: 500 uL
Supplier:
Biotium
Description:
EMI1 Monoclonal antibody, Clone: EMI1/1176, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF647, Immunogen: Recom fragment of human EMI1 protein, Synonyms: Early Mitotic Inhibitor-1 (EMI1), FBX5, Fbxo31, Application: IF, IHC, Size: 500 uL
Supplier:
Biotium
Description:
This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Supplier:
Biotium
Description:
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Supplier:
Biotium
Description:
MHC II (HLA-DP), Monoclonal antibody, Clone: Bra-14, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Human REH cells, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 500uL
Supplier:
Biotium
Description:
Insulin, Monoclonal antibody, Clone: 2D11-H5, Host: Mouse, Species reactivity: Mouse, Pig, Cow, Human, Rabbit, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Purified pig insulin, conjugated to KLH, Synonyms: IDDM2, ILPR, IRDN, MODY10, Proinsulin, Application: IF, Size: 100uL
Catalog Number:
(10119-232)
Supplier:
Biotium
Description:
Secondary, Host species: Goat; Reactivity (target): Rabbit IgG; Size: 1mL; Concentration: 1 mg/mL; HRP conjugates could be used for Western Blot, ELISA, immunohistochemistry and other standard immunoassay applications.
Supplier:
Biotium
Description:
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Supplier:
Biotium
Description:
PAX7, Monoclonal antibody, Clone: PAX7/1187, Host: Mouse, Species reactivity: Mouse, Zebrafish, Rat, Human, Chicken, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recombinant fragment (aa300-600) of human PAX7 protein, Synonyms: Paired box gene 7, Size: 500uL
Supplier:
Biotium
Description:
This antibody recognizes a protein of 33-55 kDa, identified as CD53 (Workshop V; Code CD53.1). CD53 is expressed on monocytes, and macrophages, granulocytes, dendritic cells, osteoblasts and osteoclasts, NK cells, and on T- and B-cells from every stage of differentiation but is absent from platelets, erythrocytes, and non-haemopoietic cells. CD53 is a member of a family of tetraspan transmembrane proteins, including CD9, CD37, CD63, CD81, and CD82. It associates with integrins, MHC class II molecules, and a tyrosine phosphatase and plays a role in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. Defects of CD53 expression on neutrophils appear to be related with recurrent infectious diseases. Cross-linking CD53 using CD53 antibodies led to cytoplasmic calcium fluxes in B cells, monocytes, and granulocytes and activation of the monocyte oxidative burst.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Supplier:
Biotium
Description:
with the green fluorescent dye CF488A. CF488A is a superior alternative to FITC (or fluorescein) due to its exceptional brightness and photostability. CF488A is comparably bright and photostable to Alexa Fluor 488, and more specific.
Supplier:
Biotium
Description:
HER-2 / CD340, Monoclonal antibody, Clone: HRB2/282, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recombinant intracellular domain of human HER-2 protein, Synonyms: p185, CD340, Verb b2, Size: 500uL
Supplier:
Biotium
Description:
Anti-IgG Rabbit Polyclonal Antibody (CFâ„¢ 555)
Supplier:
Biotium
Description:
MHC II (HLA-DQ), Monoclonal antibody, Clone: SPV-L3, Host: Mouse, Species reactivity: Human, Pig, Isotype: IgG2a, kappa, Conjugate: purified, Immunogen: T4-positive CTL clone HG-38, Application: Immunofluorescence, Flow cytometry, Size: 500uL
Supplier:
Biotium
Description:
This antibody recognizes a myeloid associated differentiation antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of human and monkey myeloid cells. This MAb is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.
Supplier:
Biotium
Description:
MHC II (HLA-DP), Monoclonal antibody, Clone: Bra-14, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Human REH cells, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 500uL
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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