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BIOTIUM, INC


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Supplier:  Biotium
Description:   Kappa Light Chain, Monoclonal antibody, Clone: L1C1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1), Synonyms: Ig Kappa Chain C Region; IGKC, Size: 500uL
Supplier:  Biotium
Description:   Cyclin B1 Monoclonal antibody, Clone: CCNB1/1098, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recom human full-length CCNB1 protein, Synonyms: CCNB, CCNB1, Application: IF, IHC, FC, Size: 500 uL
Supplier:  Biotium
Description:   P57 / KIP2, Monoclonal antibody, Clone: KIP2/880, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recombinant human p57Kip2 protein, Synonyms: Beckwith Wiedemann syndrome (WBS); BWCR, Application: IF, IHC, Size: 100uL
Supplier:  Biotium
Description:   Insulin, Monoclonal antibody, Clone: 2D11-H5, Host: Mouse, Species reactivity: Mouse, Pig, Cow, Human, Rabbit, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Purified pig insulin, conjugated to KLH, Synonyms: IDDM2, ILPR, IRDN, MODY10, Application: IF, Size: 500uL
Supplier:  Biotium
Description:   CD309, also known as VEGFR2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGFR2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Supplier:  Biotium
Description:   KBA.62 is a novel anti-melanoma antibody. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, it reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes. KBA.62 antibody is useful in identifying malignant melanomas. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, sarcomas, spindle cell carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immuno-reacts with antibody to S-100 protein and with KBA.62 antibody is, with rare exception, a melanoma. Anti-KBA.62 is a useful additional marker for melanoma, specifically in desmoplastic/spindle cell cases and in the context of micro-metastasis in sentinel lymph node.

Supplier:  Biotium
Description:   Major Vault Protein (MVP), Monoclonal antibody, Clone: 1014, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, BSA-free, Immunogen: Proteins precipitated from human breast cancer MCF-7 cells, Synonyms: Lung resistance-related protein, Size: 50 uL
Supplier:  Biotium
Description:   This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Supplier:  Biotium
Description:   Phosphotyrosine, Monoclonal antibody, Clone: PY20, Host: Mouse, Species reactivity: All species, Isotype: IgG2b, Conjugate: CF647, Immunogen: Phosphotyrosine conjugated to KLH, Synonyms: P-Tyr, Application: Immunofluorescence, Size: 100uL
Supplier:  Biotium
Description:   PathoGreen histofluorescent stain is an anionic green fluorescent dye functionality similar to Fluoro-Jade dyes.
Supplier:  Biotium
Description:   PTH / Parathyroid Hormone (N-Terminal), Monoclonal antibody, Clone: PTH/1174, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF594, Immunogen: synthetic peptide from N-terminal of PTH polypeptide, Synonyms: Parathyrin, Size: 100uL
Supplier:  Biotium
Description:   Insulin, Monoclonal antibody, Clone: E2-E3, Host: Mouse, Species reactivity: Mouse, Pig, Cow, Human, Rabbit, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Purified pig insulin, conjugated to KLH, Synonyms: IDDM2, ILPR, IRDN, MODY10, Proinsulin, Application: IF, Size: 500uL
Supplier:  Biotium
Description:   CD5 Monoclonal antibody, Clone: C5/473 + CD5/54/F6, Host: Mouse, Species reactivity: Rabbit, Cow, Rat, Human, Isotype: IgG2a &IgG1, K, Conjugate: biotin, Immunogen: peptide, Synonyms: CD5 antigen (p56 62), LEU1, Application: IF, Size: 500 uL
Supplier:  Biotium
Description:   Von Willebrand Factor, Monoclonal antibody, Clone: 3E2D10, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recombinant human vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Application: IF, Size: 100uL
Supplier:  Biotium
Description:   VEGFR2 / Flk-1 / KDR3 / CD309, Monoclonal antibody, Clone: KDR657, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recombinant human VEGF-R2 protein, Application: Immunofluorescence, Flow cytometry, Size: 100uL
Supplier:  Biotium
Description:   This MAb reacts with a 200 kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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