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BIOTIUM, INC
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BIOTIUM, INC
Supplier:
Biotium
Description:
P21 / WAF1, Monoclonal antibody, Clone: CIP1/823, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF594, Immunogen: Recombinant full-length human CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2), Application: IF, IHC, Size: 100uL
Supplier:
Biotium
Description:
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 alpha chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cell express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Supplier:
Biotium
Description:
HLA-Aw32 & HLA-A25 (MHC I), Monoclonal antibody, Clone: CATA-1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Human blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2, DRw10, Synonym: HLA-A, Size: 500uL
Supplier:
Biotium
Description:
This antibody recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. This MAb can be applied to test complement activation in pseudo-allergic reactions to acetylsalicylic acid and to test for measles virus infection of cells.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.
Catalog Number:
(89493-170)
Supplier:
Biotium
Description:
Anti-IgG Donkey Antibody (CFâ„¢ 568)
Supplier:
Biotium
Description:
Smooth Muscle Actin, Monoclonal antibody, Clone: 1A4, Host: Rat, Species reactivity: Human, Rat, Isotype: IgG's, Conjugate: CF647, Immunogen: N-Terminal decapeptide of alpha smooth muscle isoform of actin and conjugated to KLH (1A4), Application: IF, Size: 500uL
Supplier:
Biotium
Description:
Cyclin B1 Monoclonal antibody, Clone: CCNB1/1098, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recom human full-length CCNB1 protein, Synonyms: CCNB, CCNB1, Application: IF, IHC, FC, Size: 500 uL
Supplier:
Biotium
Description:
This product is prepared by labeling IgG with CF350. CF350 is a blue fluorescent dye spectrally similar to AMCA. However, compared to AMCA, CF350 is more water-soluble, more photostable and at least 50% more fluorescent on proteins.
Supplier:
Biotium
Description:
Cytokeratin 10 Monoclonal antibody, Clone: LH2, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG2a, kappa, Conjugate: biotin, Immunogen: Skin extract of a human Psoriasis patient, Synonyms: BCIE, BIE, EHK, Application: IF, IHC, FC, Size: 100uL
Supplier:
Biotium
Description:
CD2 Monoclonal antibody, Clone: UMCD2, Host: Mouse, Conjugate: CF405S, Species reactivity: Human, Immunogen: Human Thymocytes/Sezary T cells, Isotype: IgG's, Synonyms: Erythrocyte receptor; LFA-2; LFA-3 receptor; Ly-37, Application: Flow Cytometry, Size: 500 uL
Catalog Number:
(89493-400)
Supplier:
Biotium
Description:
Anti-IgG Donkey Polyclonal Antibody (CFâ„¢ 647)
Catalog Number:
(75891-886)
Supplier:
Biotium
Description:
This antibody recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
Supplier:
Biotium
Description:
Mucin 1 / EMA / Episialin / CD227, Monoclonal antibody, Clone: GP1.4 + E29, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Human milk-fat globule membranes, Application: IF, Size: 500uL
Supplier:
Biotium
Description:
This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGF alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.
Catalog Number:
(75973-044)
Supplier:
Biotium
Description:
PTH / Parathyroid Hormone (N-Terminal), Monoclonal antibody, Clone: 3H9, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, BSA-free, Immunogen: synthetic peptide from N-terminal of PTH polypeptide, Synonyms: Parathyrin, Size: 50 uL
Catalog Number:
(89493-518)
Supplier:
Biotium
Description:
Anti-IgG Goat Polyclonal Antibody (CFâ„¢ 405M)
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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