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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

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Supplier:  Southern Biotechnology
Description:   Biotin Anti-Human IgG3 Hinge antibody for use in ELISA, flow cytometry, immunohistochemistry, western blotting, immunoprecipitation, ELISpot, and multiplex assays.

Supplier:  Southern Biotechnology
Description:   Goat F(ab’)2 Anti-Mouse IgM-Alexa Fluor 555 antibody with minimal reactivity to human proteins for use in immunohistochemistry / immunocytochemistry assays.
Supplier:  Southern Biotechnology
Description:   CD74 represents a type II integral membrane protein known as MHC class II-associated invariant chain. It is moderately expressed on B cells and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells, and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of class II molecules on the cell surface.
Supplier:  Southern Biotechnology
Description:   Goat Anti-Hamster IgG(H+L)-HRP antibody with minimal reactivity to mouse and rat proteins for use in ELISA, immunohistochemistry, and western blotting assays.
Catalog Number: (100242-476)

Supplier:  Southern Biotechnology
Description:   Purified Goat Anti-Mouse IgG antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISpot, and multiplex assays.

Supplier:  Southern Biotechnology
Description:   Goat Anti-Human Lambda-Alexa Fluor 488 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

Supplier:  Southern Biotechnology
Description:   CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
Supplier:  Southern Biotechnology
Description:   CD71 is a 95 kDa type II heterodimeric transmembrane glycoprotein that is the receptor for transferrin. CD71 expression is very low on resting leukocytes but is upregulated upon activation. CD71 plays a critical role in cell proliferation by controlling the supply of iron which is essential for many metabolic pathways through the binding and endocytosis of transferrin.
Catalog Number: (103264-420)

Supplier:  Southern Biotechnology
Description:   Purified Goat Anti-Mouse IgG(H+L) antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA and immunocytochemistry assays.
Supplier:  Southern Biotechnology
Description:   Goat Anti-Hamster IgG(H+L)-HRP antibody for use in ELISA and western blotting assays.
Catalog Number: (103264-488)

Supplier:  Southern Biotechnology
Description:   Purified Anti-Mouse IgG1 antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.
Supplier:  Southern Biotechnology
Description:   CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a costimulatory receptor involved in many, but not all, T-cell independent immune responses.

Supplier:  Southern Biotechnology
Description:   CD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first becomes detectable on a subset of small pre-B II cells in bone marrow with the levels of CD40 expression increasing thereafter during B cell maturation. Immature B cells (IgM+IgDloB220lo) express intermediate levels of CD40, whereas mature B cells (IgM+IgDhiB220hi) express high levels. CD40 has a central role in B cell growth and differentiation, and signaling through CD40 in combination with IL-4 reportedly induces immunoglobulin isotype switching and secretion of IgE. The agonistic 1C10 antibody closely resembles gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors.

Supplier:  Southern Biotechnology
Description:   Purified Anti-Human IgG2 Fc antibody for use in ELISA, flow cytometry, immunocytochemistry, western blotting, ELISpot, and multiplex assays.
Catalog Number: (100244-370)

Supplier:  Southern Biotechnology
Description:   Purified Goat Anti-Human Lambda antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, ELISpot, and stimulation assays and for immobilization in surface plasmon resonance.
Supplier:  Southern Biotechnology
Description:   CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR).
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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