You Searched For: OPTEM

Catalog Number: (103259-882)

Supplier: Southern Biotechnology

Description: CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.

Catalog Number: (103264-358)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgM-Alexa Fluor 647 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

Catalog Number: (103264-444)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG2c-FITC for use in fluorescent assays.

Catalog Number: (103264-712)

Supplier: Southern Biotechnology

Description: Goat Anti-Human IgG Fc-HRP antibody with minimal reactivity to rabbit, mouse, rat, bovine, horse, hamster, goat, sheep, chicken, and guinea pig serum proteins for use in ELISA assays.

Catalog Number: (103264-190)

Supplier: Southern Biotechnology

Description: Rabbit IgG-Biotin for use as a control in flow cytometry and immunohistochemistry / immunocytochemistry assays.

Catalog Number: (103259-720)

Supplier: Southern Biotechnology

Description: Rat IgG2c-FITC for use as a control in flow cytometry assays.

Catalog Number: (103264-344)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG Fab-FITC antibody for use in fluorescent assays.

Catalog Number: (103264-390)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG Fc-FITC antibody for use in fluorescent assays including western blotting assays.

Catalog Number: (103264-412)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG(H+L)-PE antibody for use in fluorescent assays.

Catalog Number: (103264-400)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG Fc-Alexa Fluor 647 antibody for use in fluorescent assays including western blotting assays.

Catalog Number: (103265-604)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG1-Alexa Fluor 647 antibody for use in immunocytochemistry and fluorescent assays.

Catalog Number: (103259-984)

Supplier: Southern Biotechnology

Description: Goat Anti-Human IgG Fc-PE antibody for use in fluorescent assays.

Catalog Number: (103259-700)

Supplier: Southern Biotechnology

Description: Rat IgG2a-Alexa Fluor 488 for use as a control in flow cytometry and immunohistochemistry assays.

Catalog Number: (103259-770)

Supplier: Southern Biotechnology

Description: Purified Goat Anti-Mouse IgG2c antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA assays.

Catalog Number: (103259-666)

Supplier: Southern Biotechnology

Description: Interleukin-33 (IL-33), also known as NF-HEV, is a 30 kDa protein and a member of the IL-1 family. This pro-inflammatory cytokine is produced by a variety of cells but is primarily expressed by endothelial and smooth muscle cells in the vasculature and airways. IL-33 binds to the ST2 receptor on target cells which results in the activation of multiple signaling pathways including NF-κB and MAP kinases. Studies have shown that IL-33 promotes T helper type 2 (Th2) cell-mediated immune responses and upregulates production of Th2 associated cytokines including IL-4, IL-5, and IL-13. In vivo administration of this cytokine in mice results in eosinophilia and splenomegaly as well as induced severe pathological changes in the lungs, gastrointestinal tract, and other mucosal organs.

Catalog Number: (103264-924)

Supplier: Southern Biotechnology

Description: The SBA Clonotyping System-C57BL/6-AP kit is designed for the isotyping of C57BL/6 mouse monoclonal antibodies. It contains 2.5 mg of capture antibody and 1.0 mL of AP conjugated anti-mouse Ig, mouse IgA, mouse IgG1, mouse IgG2b, mouse IgG2c, mouse IgG3, mouse IgM, and pNPP substrate. The kit may also be utilized for quantitative studies of mouse immunoglobulins in samples such as serum, supernatant, and ascites when used in conjunction with the C57BL/6 Mouse Immunoglobulin Panel (SB Cat. No. 5300-01B).