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DIAGNOSTIC BIOSYSTEMS INC
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DIAGNOSTIC BIOSYSTEMS INC
Supplier:
Diagnostic Biosystems
Description:
This antibody stains a 60 kDa peptide in human lymphoblasts. TdT is present in the cells during immunoglobulin gene rearrangement and plays an important role in lymphocyte maturation. TdT marks both T and B immature lymphocytes normally found in thymus and bone marrow.
Supplier:
Diagnostic Biosystems
Description:
Napsin is found in two isoforms, A and B, with highly homologous gene sequences. Napsin A has a molecular weight of 35.0 kDa and is also known as TA02. Napsin A is an aspartic proteinase which is expressed in the lung and involved in processing surfactant protein B (SP-B). It is also expressed in the kidney. This antibody may be a useful tool as a tumor marker for primary lung adenocarcinoma. Napsin expression correlates with the differentiation grade of lung adenocarcinoma.
Supplier:
Diagnostic Biosystems
Description:
PermaBlue/HRP is a substrate-chromogen system designed to be used for either IHC or ISH when utilizing horseradish peroxidase
Supplier:
Diagnostic Biosystems
Description:
Monoclonal anti-smooth muscle myosin reacts with myosin heavy chain polypeptides of 200 and 204 kDa. It does not react with skeletal, cardiac, or non-muscle myosin. In immunohistochemistry it stains vascular and visceral smooth muscle cells and cells that have smooth muscle-like characteristics.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with the c-erbB-2 oncoprotein, a 190 kDa protein. The proto-oncogene for c-erbB-2 is located on the human chromosome 17, band 21. It has structural similarities to EGFR. Several studies have indicated that c-erbB-2 may be a good indicator of the prognosis of human carcinomas in the breast, ovary, uterus and gastrointestinal tract.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with pan cadherin with a distinct 135 kDa band from a wide variety of tissues. Cadherins are members of a multigene family of single chain glycoprotein receptors mediating Ca2+ dependent cell-cell adhesion.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with a neuraminidase sensitive oligosaccharide side chain of a glycoconjugate present in immature melanosomes. It reacts with junctional and blue nevus cells. Non-melanocytic cells are negative.
Supplier:
Diagnostic Biosystems
Description:
This buffer is a concentrated antigen unmasking solution and is free from heavy metals
Catalog Number:
(99990-048)
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with the human C1q complement. Traces of contaminating antibodies have been removed by solid phase absorption with human plasma proteins. This antibody is well suited for tissue section staining but may also be used for other applications.
Supplier:
Diagnostic Biosystems
Description:
Cloneac-1A1 .5Ml
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes human retinoblastoma gene protein. Rb gene, a prototype of tumor suppressor genes, has been associated with development and/or progression of bladder cancer as well as sarcoma and small cell lung cancer. Functional Rb gene loss has been reported to occur in bladder cancer and osteosarcoma. A significantly poorer tumor-free survival rate was noted for those patients who had a tumor with an altered Rb protein with or without vascular invasion.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with the terminal globular domain of the A chain. The staining with this antibody is sensitive to fixation of paraffin tissues and use of proteolytic enzymatic treatment.
Supplier:
Diagnostic Biosystems
Description:
Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of Cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. It is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to Cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones.
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific to a cluster of proteins between 70 to 80 kDa known as tyrosinase. This antibody does not show any cross-reaction with MAGE-1 and tyrosinase-related protein-1, TRP-1/gp75. Staining of melanomas with this antibody showed tyrosinase in melanotic as well as amelanotic variants.
Catalog Number:
(76634-346)
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes keratin polypeptide of 54 kDa. It stains a number of epithelial cells including ductal and glandular epithelia. Stratified squamous epithelia are positive but transitional epithelium of the urinary tract does not show any staining. This antibody labels adenocarcinomas and transitional carcinomas but does not react with squamous cell carcinomas.
Catalog Number:
(76633-310)
Supplier:
Diagnostic Biosystems
Description:
This antibody is specific against an epitope located on the β chain (i.e., in S-100a and S-100b) but not on the α chain of S-100 (i.e., in S-100a and S-100ao). This antibody can be used to localize S-100a and S-100b in various tissue sections.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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