You Searched For: DIAGNOSTIC BIOSYSTEMS INC

Supplier: Diagnostic Biosystems

Description: Clone number R1/69, This antibody reacts with the heavy chain present in all types of human IgM. It stains B cell follicles in human lymphoid tissues. In lymphoid tissues, IgM containing plasma cells stain strongly but immune complexes are usually undetectable.

Catalog Number: (76634-546)

Supplier: Diagnostic Biosystems

Description: This antibody reacts specifically with sialyl Lewisa and recognizes an epitope being designated CA 19-9. It does not cross-reacts with Lewisa and Lewisb. CA 19-9 has been shown to be useful marker in the diagnosis and management of gastrointestinal cancers.

Catalog Number: (76634-638)

Supplier: Diagnostic Biosystems

Description: This antibody reacts with HSV type I specific antigens and with antigens common to HSV type I and II virus. It reacts with all the major glycoproteins present in the viral envelope as well as with at least one core protein.

Catalog Number: (76634-320)

Supplier: Diagnostic Biosystems

Description: This antibody reacts with a glycoprotein of 110 kDa, expressed as intracytoplasmic molecule. It stains macrophages in a wide variety of tissues. Myeloid precursor cells and peripheral granulocytes are negative. The PG-M1 differs from EMB11 (CD68) because of its non-reactivity with granulocytes and their precursor cells.

Catalog Number: (95027-186)

Supplier: Diagnostic Biosystems

Description: This kit stains Lepra bacillus in paraffin tissue sections

Catalog Number: (76634-396)

Supplier: Diagnostic Biosystems

Description: This antibody is specific to a membrane glycoprotein of 45 kDa, designated as CD23. CD23 is found on a subpopulation of peripheral blood cells, B lymphocytes and on EBV transformed B lymphoblastoid cell lines. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemias.

Catalog Number: (76634-384)

Supplier: Diagnostic Biosystems

Description: Epithelial antigen is a cell surface glycoprotein and is broadly distributed in epithelial cells and displays a highly conserved expression in carcinomas. Epithelial antigen has been shown to play an important role as a tumor cell marker in lymph nodes from patients with esophageal carcinoma. Epithelial antigen can be used to distinguish between basal cell and basosquamous carcinomas and squamous cell carcinoma of the skin.

Supplier: Diagnostic Biosystems

Description: This antibody reacts with a 180 kDa protein, known as Flk-1, KDR or vascular endothelial growth factor receptor 2 (VEGFR2). Flk-1 is a cell membrane receptor kinase. Flk-1 is a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis.

Supplier: Diagnostic Biosystems

Description: This antibody reacts with a 77-85 kDa protein known as transglutaminase II (TGase II). TGase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. Different tissue and cell types express varying amounts of tissue transglutaminase.

Supplier: Diagnostic Biosystems

Description: O(6)-methylguanine-DNA-methyltransferase (MGMT) is a 22 kDa human DNA repair protein that removes O(6)-alkylguanine DNA adducts. MGMT acts as a suicide acceptor protein repairing the DNA by accepting alkyl groups and consequently inactivating itself. This antibody stains all mantle zone lymphocytes and 50% of germinal center lymphocytes. Basaloid epithelial cells of tonsil squamous mucosa are also stained positive with this antibody.

Supplier: Diagnostic Biosystems

Description: This antibody is specific to 46 kDa cytokeratin protein designated cytokeratin 17. It reacts with basal cells in complex epithelia and reacts strongly with squamous cell carcinomas.

Supplier: Diagnostic Biosystems

Description: This antibody reacts with HSV type I specific antigens and with antigens common to HSV type I and II virus. It reacts with all the major glycoproteins present in the viral envelope as well as with at least one core protein.

Catalog Number: (99990-060)

Supplier: Diagnostic Biosystems

Description: Primary antibody diluent is specifically designed for diluting primary antibodies for immunohistochemistry. Monoclonal and polyclonal antibodies can be diluted in this buffer.

Supplier: Diagnostic Biosystems

Description: 31472488

Supplier: Diagnostic Biosystems

Description: This antibody reacts with wild as well as mutant types of P53 protein. It recognizes an epitope in the N-terminus of P53 protein, known to reside between amino acids 35 to 45. This antibody can be demonstrated in 22 to 76% of the colon, stomach, bladder, breast, lung and testes cancers.

Supplier: Diagnostic Biosystems

Description: Caspase 1 and is expressed as a proenzyme in many tissues. Active Caspase 1 is a tetramer of two subunits p10 and p20 in 2:2 ratio. Overexpression of caspase 1 can induce apoptosis in fibroblast, which can be inhibited by overexpression of Crm A, a protein from pox virus.