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DIAGNOSTIC BIOSYSTEMS INC
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DIAGNOSTIC BIOSYSTEMS INC
Catalog Number:
(99990-842)
Supplier:
Diagnostic Biosystems
Description:
Clone number UCHL1, This antibody reacts with a 180 kD glycoprotein of CD45 family, occurring on most thymocytes and activated T cells but only on the portion of the resting T cells. It reacts with most thymocytes, a subpopulation of resting cells within both the CD4 and CD8 subsets and mature activated T cells.
Supplier:
Diagnostic Biosystems
Description:
The BCL-2 product is considered to act as an inhibitor of apoptosis. BCL-2 expression is inhibited in germinal centers where apoptosis forms part of the B cell production pathway. Reactive follicles show no staining for BCL-2, whereas the cells in neoplastic follicles exhibit membrane staining. BCL-2 α oncoprotein has been shown to inhibit apoptosis.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with chains of human IgA. This antibody has been adsorbed to a very high level of specificity.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Mast cells contain a number of preformed chemicals mediators such as histamine, chymase, carboxypeptidase, and proteolytic tryptase. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation.
Supplier:
Diagnostic Biosystems
Description:
Steptavidin-conjugted Alkaline Phosphatase. Ready To Use Immunostaining Kit Component
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts specifically with a 32 kDa protein similar to the CD8 molecule
Catalog Number:
(76633-446)
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes heavy chain of human skeletal myosin. It does not stain cardiac or smooth muscle myosin. This antibody stains the fast twitch (type II) isomyosin molecule.
Catalog Number:
(76634-328)
Supplier:
Diagnostic Biosystems
Description:
This antibody recognizes cytokeratin polypeptides ranging from 40 to 58 kDa, corresponding to cytokeratins 5, 6, 8,17 and 19. It shows a broad pattern of reactivity with human epithelial tissues from simple glandular epithelia to stratified squamous epithelia, like epidermis, mammary gland ducts and tracheal epithelium.
Catalog Number:
(76634-792)
Supplier:
Diagnostic Biosystems
Description:
SOX-10, a member of the sex-determining region Y-related HMG-box family, is a transcription factor that is expressed in pre-migratory and migrating neural crest cells. Following migration it remains expressed in cells destined for glial, schwannian, and melanocytic differentiation. SOX10 is widely expressed in normal human tissues including melanocytes and breast tissue. SOX10 is also an important marker in malignant tumors such as melanoma, and breast carcinomas of basal-like and triple negative type, gliomas, and benign tumors such as schwannomas. More importantly, SOX10 has been shown to be expressed in 97 to 100% of desmoplastic and spindle cell melanomas and has also been shown to be expressed in 100% of nevi. Spindle cell and desmoplastic melanomas are rare variants of invasive cutaneous melanoma, with an annual incidence rate of approximately 2 per 100,000. The majority of oligodendrogliomas and a large percentage of astrocytomas and poorly differentiated glioblastomas have also been shown to express SOX10.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with a 92 kDa pro form and 86 kDa active form of MMP-9. MMPs are proteolytic enzymes capable of degrading connective tissue components. MMPs play a crucial role in tumor cell invasion and metastasis.
Catalog Number:
(99991-044)
Supplier:
Diagnostic Biosystems
Description:
Rabbit, This antibody reacts with intracytoplasmic portion of the CD3 antigen on the T cells. It stains T cells in cortex as well as medulla of the thymus and lymphoid tissues. This antibody also labels T cell neoplasm, malignant histiocytes and in Hodgkin's disease.
Supplier:
Diagnostic Biosystems
Description:
Negative controls are used to determine the specificity of an antibody. No staining should be observed when the primary antibody is omitted.This product is specifically designed to work with rabbit, mouse and goat antibodies. The Broad Spectrum Negative Control has been titered to work with Polymer-based Secondary Systems in manual and automated IHC platforms.
Catalog Number:
(95027-178)
Supplier:
Diagnostic Biosystems
Description:
The Colloidal Iron Stain Kit is designed for the histological visualization of acid mucopolysaccharides.
Supplier:
Diagnostic Biosystems
Description:
Ki-67 is a nuclear protein, which is expressed in proliferating cells. Ki-67 is preferentially expressed during late G1-, S-, M-, and G2-phases of the cell cycle, while cells in the G0 (quiescent) phase are negative for this protein.
Supplier:
Diagnostic Biosystems
Description:
This antibody reacts with a 100 kDa glycoprotein expressed by endothelial cells and 130 kDa glycoprotein present in platelets. It stains endothelial cells in normal as well as malignant tissues.
Catalog Number:
(76634-530)
Supplier:
Diagnostic Biosystems
Description:
Podoplanin is a 38 kDa membrane mucoprotein originally detected on the surface of rat podocytes .The antibody against podoplanin (D2-40) reacts to a 40 kDA sialogylcoprotein found on lymphatic endothelium, fetal testis, and on the surface of testicular germ cell tumors. Podoplanin can be used to assist pathologists in identifying lymphatic endothelium to determine lymphatic invasion and also can be used to help differentiate mesothelioma from adenocarcinoma.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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