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Van Der Voort Lucht en Milieu Amste
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Van Der Voort Lucht en Milieu Amste
Catalog Number:
(102513-072)
Supplier:
Adipogen
Description:
Human CD152 (CTLA-4) is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation.
Supplier:
Adipogen
Description:
Fluorogenic tetrapeptide substrate for ubiquitin C-terminal hydrolases (UCHs, e.g. UCHL3) and isopeptidase T. LRGG is the preferred substrate sequence of the human deSUMOylating enzymes SENP6 and SENP7. Excitation: 380nm. Emission: 460nm.
Catalog Number:
(102513-406)
Supplier:
Adipogen
Description:
CD4 binds to MHC Class II expressed by antigen presenting cells, facilitating T cell receptor signaling.
Catalog Number:
(102514-702)
Supplier:
Adipogen
Description:
anti-EGFP, monoclonal antibody (recombinant) (G3) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
Catalog Number:
(102514-114)
Supplier:
Adipogen
Description:
ANGPTL7 is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterized as a potent target gene of the WNT/ beta-catenin signaling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine.
Catalog Number:
(102512-732)
Supplier:
Adipogen
Description:
Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.
Supplier:
Adipogen
Description:
Fluorescent dye (label, probe, stain).
Catalog Number:
(102979-292)
Supplier:
Adipogen
Description:
Oxidative damage to lipids (lipid peroxidation) has been found to play an important role in various disease and aging processes. During early stages of lipid peroxidation, lipid hydroperoxides (LOOH) are formed. These can react additionally to form later stage end products such as malondialdehyde (MDA) and hydroxynonenal (HNE). LOOH is measured to quantify early stage or acute lipid peroxidation while MDA is commonly measured to quantify late stage or chronic lipid peroxidation. More recently, it has been reported that 13-hydroperoxyoctadecanoic acid (13-HPODE), a precursor to 13-hydroxyoctadecanoic acid (13-HODE) can react with proteins to form measurable adducts by covalently binding to specific amino acid residues. The Hexanoyl-Lysine (HEL) adduct is formed upon oxidative modification of omega-6 fatty acids such as linoleic acid, the predominant polyunsaturated fatty acid (PUFA) in the human diet, and arachidonic acid. HEL may be another useful biomarker for detecting and quantifying the earlier stages of lipid peroxidation.
Supplier:
Adipogen
Description:
Anti-inflammatory and anti-arthritic agent
Catalog Number:
(102512-510)
Supplier:
Adipogen
Description:
Human CD60 antigen is a glycolipid determinant found on about 30% of peripheral blood T cells. The glycolipid determinant is linked to a glycoprotein which can transduce activation signals.
Catalog Number:
(102988-356)
Supplier:
Adipogen
Description:
Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has nanomolar binding affinity to PPARgamma and micromolar binding to the isotypes PPARalpha and PPARbeta/delta. Glucose-lowering agent. Improves insulin sensitivity, glucose tolerance and blood lipid variables without increase of fat storage or hepatoxicity. Shows potent PPARgamma-dependent anti-inflammatory activity. Potent NF-kappaB activation inhibitor by the suppression of IkappaBalpha degradation, p65 nuclear translocation and DNA-binding activity. Antimicrobial agent.
Catalog Number:
(102512-940)
Supplier:
Adipogen
Description:
Human CD98 (4F2) is a heterodimeric glycoproein expressed on monocytes and activated cells. All cultured human cell lines tested express CD98. CD98 heavy chain mediates adhesion induced activation through integrin signaling.
Supplier:
Adipogen
Description:
Polylactides (PLA) used in material sciences. Polymer. Lactide and Glycolide Polymers.
Catalog Number:
(102512-214)
Supplier:
Adipogen
Description:
Human CD30 is a member of the TNF receptor family and is expressed on mitogen activated B and T cells.
Supplier:
Adipogen
Description:
Hydroxy fatty acid used to study its role in biological processes such as oxidative stress, inflammation and insulin resistance. Used in endotoxin and lipid A research, since it is one of two major components of bacterial Lipid A. Shows antifungal activity. Compound could be used as analytical reference in assaying food samples.
Supplier:
Adipogen
Description:
Intercalating probe for nucleic acids. Other applications include the determination of cationic surfactants.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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