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2-(4-Aminophenyl)-2-methylpropanenitrile
Catalog Number:
(10110-476)
Supplier:
Prosci
Description:
COL4A3BP is a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport.This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Two transcripts exist for this gene.
Catalog Number:
(10403-636)
Supplier:
Bioss
Description:
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
Catalog Number:
(10403-638)
Supplier:
Bioss
Description:
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
Catalog Number:
(10783-918)
Supplier:
CHI Scientific
Description:
Kit PrimaCell*7 Mouse Kidney OptiTDS*7: Tissue Dissociation System, A mixture of collagenase I, collagenase III, collagenase IV, collagenase, and trypsin.
Catalog Number:
(10786-270)
Supplier:
CHI Scientific
Description:
Kit PrimaCell* Mouse Aorta OptiTDS*, Tissue Dissociation System, A mixture of collagenase I, collagenase III, collagenase III and collagenase IV.
Catalog Number:
(10344-198)
Supplier:
Bioss
Description:
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
Catalog Number:
(76482-114)
Supplier:
AAT BIOQUEST INC
Description:
Gly-Pro-AMC is a sensitive fluorogenic substrate for detecting dipeptidyl peptidase IV (DPPIV), a serine protease that cleaves N-terminal dipeptides from polypeptides with L-proline or L-alanine at the penultimate position.
Catalog Number:
(76194-618)
Supplier:
Prosci
Description:
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Catalog Number:
(ABCA_AB210180-100U)
Supplier:
ABCAM INC.
Description:
Anti-COX IV Rabbit Monoclonal Antibody [clone: EPR9442(ABC)] (Alexa Fluor® 405)
Catalog Number:
(ABCA_AB319935-100U)
Supplier:
ABCAM INC.
Description:
Anti-beta IV Tubulin Rabbit Monoclonal Antibody [clone: EPR16776] (Alexa Fluor® 555)
Catalog Number:
(ABCA_AB321224-100U)
Supplier:
ABCAM INC.
Description:
Anti-beta IV Tubulin Rabbit Monoclonal Antibody [clone: EPR16776] (Alexa Fluor® 750)
Catalog Number:
(ABCA_AB210674-100U)
Supplier:
ABCAM INC.
Description:
Anti-COX IV Rabbit Monoclonal Antibody [clone: EPR9442(ABC)] (Alexa Fluor® 594)
Supplier:
MilliporeSigma
Description:
Quartz fine granular, Washed and calcined for analysis, Cas number: 14808-60-8, chemical Formula: SiO2, Pack size: 1KG
Catalog Number:
(10248-444)
Supplier:
Bioss
Description:
Neurexins comprise a family of neuronal cell surface proteins, which include neurexin I (NRXN1), neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV). Neurexins I-III are expressed as a and b isoforms. The a isoforms are made of three cassettes, which contain two LNS (Laminin A, Neurexins, Sex hormone-binding)-domains separated by EGF domains, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal. The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin. The b isoforms have only one LNS-domain, bind to neuroligins, and play a role in the formation and remodeling of synapes. Caspr (for Contactin-Associated Protein 1, also designated Paranodin in mouse), contains an extracellular domain similar to the other three neurexins, and binds to the surface glycoprotein Contactin. Caspr and the closely related Caspr2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. Specifically, Caspr exists at the paranodal junctions, while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region. Caspr may play a role in the communication of glial cells and neurons during development.
Catalog Number:
(10453-190)
Supplier:
Bioss
Description:
Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
Supplier:
DWK Life Sciences (KIMBLE)
Description:
Tubes feature a fire-polished top rim and uniform wall thickness for maximum heat transfer and chemical resistance.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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