3-Bromo-2-fluoro-5-nitropyridine
Supplier:
AAT BIOQUEST INC
Description:
4-Methylumbelliferyl-beta-D-galactopyranoside (MUG) is a fluorogenic MU substrate for detecting galactosidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer.
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Catalog Number:
(AAA14043-30)
Catalog Number:
(101907-330)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 054432-500MG , MDL Number: MFCD05664410
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 058859-5G , MDL Number: MFCD00052500
Catalog Number:
(80053-180)
Supplier:
MilliporeSigma
Description:
50 mg. 4-MU-a-D-Gal. White to off-white solid. Substrate for the fluorogenic assay of a-D-galactosidase. Purity: >98% by TLC. Excitation max.: 360 nm; emission max.: 440 nm. Reconstitute just prior to use. CAS 38597-12-5. Protect from light and moisure.
Catalog Number:
(77984-601)
Supplier:
LGC STANDARDS
Description:
Fostamatinib, TRC, LGC Standards
Catalog Number:
(101824-010)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 027355-500MG , MDL Number: MFCD00075006
Catalog Number:
(101928-126)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 064662-500MG , MDL Number: MFCD07782421
Catalog Number:
(TCC0549-025G)
Supplier:
TCI America
Description:
CAS Number: 1829-00-1
MDL Number: MFCD00013091 Molecular Formula: C28H21N5O6S4 Molecular Weight: 695.71 Form: Crystal Color: Yellow
Supplier:
Adipogen
Description:
Non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 µM and 2.0-28.4 µM, respectively. Naproxen is a potent, non-steroidal, non-selective anti-inflammatory compound that acts as a Cox (cyclooxygenase) inhibitor, and inhibits both Cox-1 and Cox-2. Research indicates that the S-naproxen is a more active form than the R-naproxen. The S-naproxen enantiomer was observed to inhibit platelet aggregation, and both enantiomers decrease production of thromboxane B2. Naproxen has been demonstrated to block Abeta fibril growth and form a complex with copper (II).
Supplier:
Adipogen
Description:
Antifungal and antifertility compound. Antitumor compound. PPARalpha signaling agonist. Angiogenesis inhibitor. Apoptosis and autophagy inducer. Microtubule-destabilizing agent. Anti-inflammatory. Inhibits NF-kappaB and p38 signaling. Immunosuppressive.
Supplier:
Adipogen
Description:
Antibacterial. Human collagen I synthesis inducer. Anti-wrinkle activity. Shows wound healing activity. Enhances normal human skin cell migration, attachment and growth. Suppresses collagen expression and TGF-beta/Smad signaling by inducing Smad7 and inhibiting TGF-betaRI and TGF-betaRII. Anti-inflammatory. Anti-gastric ulcer. Mitogen-activated protein kinases (MAPKs), nuclear factor-kappaB (NF-kappaB), cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOSII) expression, production of serum tumor necrosis factor (TNF-alpha) and interleukin-6 (IL-6) inhibitor. Apoptosis inducer in cancer cells. Enhances antitumor activity of vincristine in cancer cells. Might be useful in cancer chemotherapy. Anxiolytic. Antidepressant-like activity. Hepatoprotective effects. CYP2C19 and CYP3A4 inhibitor. Neuroprotective. Antileishmanial activity. cPLA2 and sPLA2 inhibitor.
Supplier:
Adipogen
Description:
Tozasertib, or VX-680, is a potent and selective inhibitor of Aurora kinases, particularly Aurora A and B. In vitro, VX-680 blocks cell cycle progression and induces apoptosis in a wide range of human tumor types at low IC(50) values (i.e. 3.38nM for human BE-13 cells, and 14.34nM for NTERA cells). Moreover, VX680, also has very potent Ki values, with inhibition constants (Ki) of 0.6, 18, and 46nM for Aurora A, B, and C, respectively. VX-680 is also effective in vivo, being used in a Caki-1 xenograft model, VX-680 demonstrated a 75.7% (P < 0.001) decrease in Caki-1 xeno-graft tumor volume with no apparent alternation in animal body weight, peripheral blood counts, or other biological parameters.
Catalog Number:
(77668-902)
Supplier:
AMBEED, INC
Description:
TES sodium salt (2-(Tris(hydroxymethyl)methylamino)ethane-1-sulfonic acid sodium salt) ≥95%
Catalog Number:
(101907-484)
Supplier:
Matrix Scientific
Description:
Matrix Scientific Part Number: 054489-500MG , MDL Number: MFCD14584785
Supplier:
AMBEED, INC
Description:
3-Acetylpyrrole, Purity: 98%, CAS Number: 1072-82-8, Appearance: Off white to Yellow-brown Solid, Storage: Sealed in dry, 2-8 C, Size: 25g
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