Proteins and Peptides
Supplier:
Bachem Americas
Description:
The neurotoxicity of the short fragment IIGLM is similar to that of amyloid β-protein (1-42) (H-1368). Aβ 31-35 induced apoptosis in undifferentiated PC 12 cells.
Supplier:
Bachem Americas
Description:
Besides deltorphins, dermorphins, dynorphins, enkephalins and endorphins, Bachem offers opioid peptides such as acetalins, BAM peptides, α-casein and gluten exorphins, endomorphins, kyotorphins, metorphamide, opiorphins, δ opioid receptor antagonists, and valorphin.
Supplier:
Bachem Americas
Description:
Vapreotide is a potent octapeptide analog of somatostatin with selectivity for the somatostatin receptor subtypes SSTR-2 and SSTR-5. It is under investigation in the management of various disorders, including esophageal variceal bleeding, gastrointestinal and pancreatic fistulas, acromegaly, carcinoid tumors, and for the prevention of postoperative complications following pancreatic surgery.
Supplier:
Bachem Americas
Description:
Bachem additionally offers deuterated phenylalanine: Fmoc-[ring-D₅]Phe-OH B-4115.
Supplier:
Bachem Americas
Description:
Antimicrobial peptides are produced by plants and most organisms throughout the animal kingdom including humans. Antimicrobial peptides protect against a broad range of infectious agents, as bacteria, fungi, and viruses. The amphibian skin is an especially rich source of antimicrobial peptides. See also the product families: Hepcidins LL-37 and Fragments Tuftsin and Analogs (subfamily).
Supplier:
Bachem Americas
Description:
Suc-ALPF-pNA, substrate for FK-506 binding proteins (FKBPs, also called macrophilins) and cyclophilins, which belong to the group of peptidyl prolyl cis-trans isomerases (PPIases). This tetrapeptide has been used for an uncoupled protease-free assay of PPIase activity.
Supplier:
Bachem Americas
Description:
See also G-4745, H-3996, the branched substrates H-2416, and L-2070, and the product families 'Glutathione-Related Peptides' and 'Ophthalmic Acid'.
Supplier:
Bachem Americas
Description:
Substrates for measuring the chymotryptic, PGPH, and tryptic acitivity of the 20S or 26S proteasome. See also the thrombin substrate I-1140.
Supplier:
Bachem Americas
Description:
5G CAS: 17343-02-1 C9H17N3O4S FW: 263.32
Supplier:
Spectrum Chemicals
Description:
Gelatin, Powder is clear, translucent, flavorless and colorless solid substance. Obtained from various animal byproducts, most often porcine-based collagen. Its uses vary from cosmetics to gelling agent in cooking as well as pharmaceutical capsules and theatrical color gel films. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
Supplier:
Bachem Americas
Description:
Peptide YY (3-36) and peptide YY are both synthesized by the gastrointestinal tract and released into the circulation after a meal. Peptide YY (3-36) is a Y₂ receptor subtype agonist, whereas peptide YY is non-selective for Y₁ and Y₂ receptor subtypes. It has been suggested that Y₁ and Y₂ receptor subtype binding affinities depend on their secondary and tertiary solution state structures.
Supplier:
MilliporeSigma
Description:
A tripeptide that serves as a component of the [gamma]-glutamyl amino acid transport system. An endogenous antioxidant that provides protection against auto-oxidation.
Supplier:
Bachem Americas
Description:
Intramolecularly quenched fluorescent substrate containing the ortho-aminobenzoyl (Abz) / N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor / acceptor pair. It corresponds to the Swedish-mutated (JMV2236) β-amyloid precursor protein (βAPP) sequence targeted by β-secretase BACE (β-site APP-cleaving activity). This FRET substrate is more selectively cleaved by BACE1 and BACE2 than by cathepsin D, a disintegrin and metalloprotease 10 (ADAM10), tumor necrosis α-converting enzyme (TACE), presenilin-1 (PS1), or presenilin-2 (PS2).
Supplier:
Bachem Americas
Description:
Potential degradation product of Ala-Gln, a glutamine source used in parenteral nutrition.
Supplier:
Bachem Americas
Description:
Also known as dioxopiperazines, piperazine-2,5-diones or DKPs. Diketopiperazines may occur as by-products during peptide synthesis or during the degradation of peptides. These cyclic dipeptides have been detected as taste-modulating compounds in food, they often show biological activity. DKPs are valuable chiral synthons, employed e.g. in Schöllkopf's versatile bislactim ether approach. They also have found use as catalysts for enantioselective synthesis, e.g. in the asymmetric Strecker reaction. See also the TRH metabolite cyclo(-His-Pro), G-1745, and cyclo(-Asp-Phe), G-1695, the major degradation product of aspartame.
Catalog Number:
(H-4904.0500BA)
Supplier:
Bachem Americas
Description:
The 38 amino acid peptide DNP, which has been originally isolated from the venom of the green mamba snake (Dendroaspis angusticeps), shares structural homology with the family of natriuretic peptides. DNP contains a 17 amino acid disulfide ring similar to ANP, BNP, and CNP, which mediate biological actions through particulate guanylyl cyclase receptors and generation of guanosine monophosphate (cGMP).
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