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Proteins and Peptides
Supplier:
Enzo Life Sciences
Description:
Produced in E. coli.
Catalog Number:
(RL009-001-C23)
Supplier:
Rockland Immunochemical
Description:
Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as Tumor Angiogenesis Factor. Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth, vascular permeability, cell migration, and endothelial cell proliferation and growth, it may play a role in stimulating vasolidation via nitric oxide-dependent pathways and in inhibition of apoptosis. VEGF binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Alternative splicing of the mRNA for VEGF-A results in several isoforms of the protein being produced. Rat and bovine VEGF are one amino acid shorter than the human factor, and the bovine and human sequences show a homology of 95 percent. In contrast to other factors mitogenic for endothelial cells such as FGF-1, FGF-2 and PDGF, VEGF is synthesized as a precursor containing a typical hydrophobic secretory signal sequence of 26 amino acids. Glycosylation is not required for efficient secretion of VEGF. VEGF121 is acidic, freely secreted, and widely expressed. This isoform is produced by alternative promoter usage and alternative initiation. It starts at an alternative upstream CUG codon and is post-translationally processed to produce the secreted VEGF peptide and a N-terminal peptide N-VEGF. The unprocessed protein and the N-VEGF peptide may localize to the nucleus, the endoplasmic reticulum and the Golgi or the extracellular matrix. Recombinant Human VEGF-121 produced in E.coli is a double, non-glycosylated, polypeptide chain containing 121 amino acids and having a molecular mass of 28423 Daltons.
Catalog Number:
(89151-830)
Supplier:
Enzo Life Sciences
Description:
Produced in CHO cells. The sequence coding for the 4 extracellular Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1.
Supplier:
Rockland Immunochemical
Description:
Recombinant Human VEGF-121 control protein
Supplier:
Rockland Immunochemical
Description:
Recombinant Human IL-10 control protein
Catalog Number:
(89151-700)
Supplier:
Enzo Life Sciences
Description:
Produced in HEK 293 cells. The extracellular domain of human TNF-R1 (aa 1-211) is fused to the Fc portion of human IgG1.
Catalog Number:
(89165-090)
Supplier:
Enzo Life Sciences
Description:
Produced in E. coli cells. Derivatised chemically, in vitro.
Catalog Number:
(89164-156)
Supplier:
Enzo Life Sciences
Description:
Produced in insect cells. Full length active enzyme.
Supplier:
MP Biomedicals
Description:
The ability of the inhibitor to inhibit the action of bovine trypsin is measured spectrophotometrically in a system in which benzoyl-arginine-ethyl ester is utilized as the typsin substrate.
Supplier:
MP Biomedicals
Description:
Elastin is highly stable and hemocompatible protein now finding use in construction of biomaterials as a result of several strategies for its solubilization. It is a structural protein which has been used in studies of Chronic obstructive pulmonary disease (COPD). It may be used to investigate why there is a lack of repair for these proteins in patients with COPD.
Catalog Number:
(RL000-006-K83)
Supplier:
Rockland Immunochemical
Description:
Histone H4 Peptide Conjugated
Catalog Number:
(IC19139101)
Supplier:
MP Biomedicals
Description:
C1q, together with C1r and C1s, in the ratio of 1:2:2, form the C1 complex which is the first component of the classical complement pathway. C1q is composed of 18 polypeptide chains (six A, six B, six C) (MW 460 kDa). All contain an 81-aa collagen-like region composed of (Gly-Xaa-Yaa) repeating sequences close to the N-terminus. Three chains (A1B1C1) form a triple helix with the C-terminus forming the globular heads which may be structurally and functionally distinct domains.
Supplier:
Enzo Life Sciences
Description:
Produced in <i>E. coli.</i> A non-glycosylated protein containing 98 amino acids.
Supplier:
MP Biomedicals
Description:
Cytochrome c is an electron-carrying mitochondrial protein. The transition of Cytochrome c between the ferrous and ferric states within the cell makes it an efficient biological electron-transporter and it plays a vital role in cellular oxidations in both plants and animals. It is generally regarded as a universal catalyst of respiration, forming an essential electron-bridge between the respirable substrates and oxygen.
Catalog Number:
(RLS00052)
Supplier:
Rockland Immunochemical
Description:
STREPTAVIDIN ATTO 488 Conjugated
Catalog Number:
(89150-322)
Supplier:
Enzo Life Sciences
Description:
Polymyxin antibiotic
Mixture of >30 compounds, primarily colistin A and B
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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