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Update to Avantor’s response to the coronavirus (COVID-19) pandemic

2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA) ≥98%

Supplier: CAYMAN CHEMICAL COMPANY, INC.
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14617-1 14617-5 14617-10 14617-25
76292-910EA 38.18 USD InStock
76292-910 76292-912 76292-914 76292-916
2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA) ≥98%
2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA)
  • A STING activator and tumor vascular disrupting agent

A tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core; potently activates the STING/TBK1/IRF3 signaling pathway in mouse leukocytes, inducing type-I-IFN production; inhibits VEGFR1 and VEGFR2 (IC50 = 119 and 11 µM, respectively)


Formula: C₁₇H₁₄O₄
Storage Temperature: Freezer
 MDL Number: MFCD00870555
CAS Number: 117570-53-3
https://qa.digitalassets.avantorsciences.com/adaptivemedia/rendition?id=0d0a68581c9c6f0e3720761413960a00db39d9bf&vid=0d0a68581c9c6f0e3720761413960a00db39d9bf&prid=web&clid=SAPDAM
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Specification Test Results
Formulation A crystalline solid
Purity ≥98%
Stability ≥ 2 years

 

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