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CAYMAN CHEMICAL COMPANY, INC.
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CAYMAN CHEMICAL COMPANY, INC.
Catalog Number:
(76544-384)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-222)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
Dimethyl biphenyl-4,4'-dicarboxylate, Purity >/=95%, CAS 792-74-5, MF: C16H14O4, MW: 270.3, Synonyms: Biphenyl dimethyl dicarboxylate, 4,4'-dimethyl ester [1,1'-biphenyl]-4,4'-dicarboxylic acid, Size: 50g
Catalog Number:
(76543-998)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-456)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-380)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
RO8191, Purity >/=98%, CAS 691868-88-9, MF: C14H5F6N5O, MW: 373.2, Synonyms: Ro 494-8191, 8-(1,3,4-oxadiazol-2-yl)-2,4-bis(trifluoromethyl)-imidazo[1,2-a][1,8]naphthyridine, Formulation: A crystalline solid, Storage: -20C, Size: 25mg
Supplier:
Cayman Chemical Company
Description:
SC-514, Purity >/=98%, CAS 354812-17-2, MF: C9H8N2OS2, MW: 224.3, Synonyms: 4-amino-[2,3'-bithiophene]-5-carboxamide, selective and reversible inhibitor of IKB kinase 2, Formulation: A crystalline solid, Size: 10mg
Catalog Number:
(76292-892)
Supplier:
Cayman Chemical Company
Description:
Cyclic GMP-AMP (cGAMP) synthase (cGAS) is a nucleotidyltransferase located in the cytosol that acts as a cytosolic DNA sensor to detect foreign DNA from microbial pathogens as part of the innate immune response. Upon binding to cytosolic DNA, cGAS produces the cyclic dinucleotide second messenger cGAMP, which activates (STING), leading to activation of the type I interferon (IFN) pathway. <em>In vitro</em>, fibroblasts, macrophages, and dendritic cells isolated from cGAS knockout (cGAS<sup>-/-</sup>) mice do not produce type I IFNs following DNA transfection or DNA virus infection. Similarly, cells containing a frame-shift mutation in the cGAS locus fail to mount an immune response to HIV and other retroviruses. <em>In vivo</em>, cGAS<sup>-/-</sup> mice infected with herpes simplex virus 1 (HSV-1) have lower levels of IFN-α and IFN-β, shorter survival times, and higher post-mortem levels of HSV-1 in the brain.
Catalog Number:
(76544-094)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-544)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76271-078)
Supplier:
Cayman Chemical Company
Description:
For A and J series prostaglandin analog screening
Catalog Number:
(76544-226)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76544-298)
Supplier:
Cayman Chemical Company
Description:
A Certified Reference Material
Catalog Number:
(76304-458)
Supplier:
Cayman Chemical Company
Description:
STING M284 variant Monoclonal Antibody, Clone: 8E7, Host: Mouse, Reactivity: Human, Isotype: IgG1, Immunogen: Synthetic peptide from the internal region of human STING protein containing the R284M mutation, Synony
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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