20449-1
20449-5
20449-10
20449-25
76292-940EA
38.18
USD
InStock
76292-940
76292-942
76292-944
76292-946
RO8191 ≥98%
RO8191
An IFNAR2 agonist with antiviral activity (EC50 = 200 nM in an anti-HCV replicon assay); exhibits 1:1 binding to the IFNAR2 extracellular domain; induces expression of IFN-stimulated genes without induction of genes encoding inflammatory cytokines and chemokines in vitro and in vivo; reduces HCV titer in HCV-infected humanized liver mice following oral administration